Radiation-induced damage to normal tissues after radiotherapy in patients treated for gynecologic tumors: Association with single nucleotide polymorphisms in XRCC1, XRCC3, and OGG1 genes and in vitro chromosomal radiosensitivity in lymphocytes

Article ID	Journal	Published Year	Pages	File Type
9872368	International Journal of Radiation OncologyBiologyPhysics	2005	10 Pages	PDF

Abstract

Conclusion: The results of the present study showed that clinical radiosensitivity is associated with an enhanced G2 chromosomal radiosensitivity and is significantly associated with a combination of different polymorphisms in DNA repair genes.

Keywords

Risk alleles Chromosomal radiosensitivity Polymorphisms DNA repair genes

Related Topics

Physical Sciences and Engineering Physics and Astronomy Radiation

Preview

Radiation-induced damage to normal tissues after radiotherapy in patients treated for gynecologic tumors: Association with single nucleotide polymorphisms in XRCC1, XRCC3, and OGG1 genes and in vitro chromosomal radiosensitivity in lymphocytes

Authors

Kim M.Sc., Marc M.D., Ph.D., Kathleen Ph.D., Rudy M.D., Anne M.D., Ph.D., Anne Ph.D., Leo M.D., Ph.D., Hubert Ph.D.,