Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9872524 | International Journal of Radiation Oncology*Biology*Physics | 2005 | 7 Pages |
Abstract
Conclusion: These preclinical results suggest that treatment with the HDAC inhibitor SAHA can enhance radiation-induced cytotoxicity in human prostate and glioma cells. We are examining the capacity of HDAC inhibitors to modulate radiation response and tumor control in animal xenograft model systems to strengthen the rationale for future clinical trial exploration.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Prakash M.D., Geetha M.D., Eric M.S., Shyh-Min Ph.D., Paul M. M.D.,