Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9872652 | International Journal of Radiation Oncology*Biology*Physics | 2005 | 7 Pages |
Abstract
In this group of clinical CT Stage N2-N3 NSCLC patients, use of FDG-PET scanning information in radiotherapy planning reduced the radiation exposure of the esophagus and lung, and thus allowed significant radiation dose escalation while respecting all relevant normal tissue constraints. This, together with a reduced risk of geographic misses using PET-CT, led to an estimated increase in TCP from 13% to 18%. The results of this modeling study support clinical trials investigating incorporation of FDG-PET information in CT-based radiotherapy planning.
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Authors
Antoinet M.D., Sebastiaan M.Sc., Monique M.D., Ph.D., Rob M.D., Ph.D., Liesbeth M.D., Ph.D., Rinus M.D., Ludy M.D., Michael M.D., Søren M. M.Sc., Ph.D., Brad M.Sc., Ph.D., Philippe M.D., Ph.D., Dirk M.D., Ph.D.,