Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9872684 | International Journal of Radiation Oncology*Biology*Physics | 2005 | 7 Pages |
Abstract
Long-term inhibition of angiogenesis after radiotherapy significantly reduced the growth rate of local recurrences but did not improve local tumor control. This indicates that recurrences after irradiation depend on vascular endothelial growth factor-driven angiogenesis, but surviving tumor cells retain their clonogenic potential during adjuvant antiangiogenic treatment with PTK787/ZK222584.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Daniel M.D., Franziska M.D., Mechthild M.D., Yvonne Schiefer, Cordelia Hoinkis, Howard D. Ph.D., Martin Ph.D., Michael M.D., Ph.D.,