Article ID Journal Published Year Pages File Type
9872721 International Journal of Radiation Oncology*Biology*Physics 2005 12 Pages PDF
Abstract
The present results suggest that TC-A and bcl-2 antisense oligonucleotides reduce radioresistance of tumor cells overexpressing Bcl-2. Therefore, a combination of radiotherapy and Bcl-2 inhibitors may prove to be a useful therapeutic approach for treating tumors that overexpress Bcl-2.
Keywords
Related Topics
Physical Sciences and Engineering Physics and Astronomy Radiation
Preview
Bcl-2 inhibitors potentiate the cytotoxic effects of radiation in Bcl-2 overexpressing radioresistant tumor cells
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