Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9879457 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2005 | 7 Pages |
Abstract
These results point at a dominant role of leukocyte CCR2 in atherogenesis, implying that CCR2 from nonleukocyte sources, like endothelial cells or smooth muscle cells, is less critical in the initiation of atherosclerosis. Pharmacological inhibition of leukocyte CCR2 function might be a promising strategy to prevent atherosclerosis.
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Authors
Jian Guo, Miranda Van Eck, Vivian de Waard, Nobuyo Maeda, G. Martin Benson, Pieter H.E. Groot, Theo J.C. Van Berkel,