Telomere length versus hormonal and bone mineral status in healthy elderly men

We found that mean TRF length was inversely correlated with age (r = −0.19; P = 0.049). Although no correlations were found with sex steroids or BMD at baseline, age corrected mean TRF length was associated with longitudinal bone loss for different distal forearm sites (P < 0.05). Further studies are required to confirm our results, yet in this study, the predictive value of telomere length for bone loss appears to be substantial, hence underscoring the role of telomere length as a biomarker of ageing phenotypes.