Article ID Journal Published Year Pages File Type
9881346 Mechanisms of Ageing and Development 2005 5 Pages PDF
Abstract
Individual organisms show marked variability in life span, even when they are of the same genotype and are raised in a common environment protected from extrinsic hazards. This intrinsic variability of life span is thought to arise from the stochastic nature of the cellular and molecular mechanisms controlling development and ageing. In this article we review what is currently understood about the factors underlying the variability of life span and consider the implications for research that aims to improve the predictability of health in old age.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Ageing
Authors
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