Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9881369 | Mechanisms of Ageing and Development | 2005 | 11 Pages |
Abstract
Moreover, in the concern of our plan to discover new genetic factors related to longevity, we explored the possibility to by-pass the need of an a-priori choice of candidate genes, extending the search to genes and genomic regions of still unknown function. Alu sequences may be considered as good markers of highly variable and potentially unstable loci in functionally important genomic regions. We extensively screened Alu-rich genomic sites and found a new genomic region associated with longevity.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Claudio Franceschi, Fabiola Olivieri, Francesca Marchegiani, Maurizio Cardelli, Luca Cavallone, Miriam Capri, Stefano Salvioli, Silvana Valensin, Giovanna De Benedictis, Angelo Di Iorio, Calogero Caruso, Giuseppe Paolisso, Daniela Monti,