| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9899157 | International Journal of Medical Microbiology | 2005 | 7 Pages |
Abstract
Helicobacter pylori is a microbial pathogen that colonises the stomach of more than half of the world's human population. H. pylori infection can induce chronic gastritis, peptic ulceration and more rarely, gastric adenocarcinoma. A prominent feature of H. pylori is the presence of a pathogenicity island (PAI) which encodes a type IV secretion system (T4SS). This review focuses on the processes of how H. pylori induces PAI-dependent epithelial cell signalling that might be of importance in gastric inflammation and the pathogenesis of neoplasia.
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Authors
Michael Naumann,