Article ID Journal Published Year Pages File Type
9908942 Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2005 9 Pages PDF
Abstract
Since genetic polymorphisms can also modify the extent of genetic damage occurring in subjects exposed to carcinogens, we measured the frequency of micronuclei in peripheral blood lymphocytes of a subgroup of MM cases. The limited number of cases (28) did not allow to observe significant effects. In conclusion, these results strengthen the hypothesis that individual susceptibility to MM can be modulated by the interaction between polymorphic genes involved in the metabolism and the intensity of asbestos exposure.
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