Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9908942 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2005 | 9 Pages |
Abstract
Since genetic polymorphisms can also modify the extent of genetic damage occurring in subjects exposed to carcinogens, we measured the frequency of micronuclei in peripheral blood lymphocytes of a subgroup of MM cases. The limited number of cases (28) did not allow to observe significant effects. In conclusion, these results strengthen the hypothesis that individual susceptibility to MM can be modulated by the interaction between polymorphic genes involved in the metabolism and the intensity of asbestos exposure.
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Authors
Monica Neri, Rosangela Filiberti, Emanuela Taioli, Seymour Garte, Valentina Paracchini, Claudia Bolognesi, Pier Aldo Canessa, Vincenzo Fontana, Giovanni Paolo Ivaldi, Anna Verna, Stefano Bonassi, Riccardo Puntoni,