| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9909107 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2005 | 15 Pages |
Abstract
Altogether the present review stresses that species differences and mechanistic data have to be taken into account and that new mechanism- and toxicokinetic-based methods and models are required for cancer risk extrapolation from high dose experimental animal data to low dose carcinogenic risks for man.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Ivonne M.C.M. Rietjens, Marelle G. Boersma, Hester van der Woude, Suzanne M.F. Jeurissen, Maaike E. Schutte, Gerrit M. Alink,