Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9909129 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2005 | 13 Pages |
Abstract
Thirteen subjects were found to carry the mutation; normals (2/9), atopics (2/10), food anaphylactics (5/11) and non-food anaphylactics (4/10). Statistical analysis of the data determined that there was no significant difference between the numbers of subjects found to carry the Asp816Val mutation in each of the groups although a trend towards an increased occurrence in anaphylactics was observed. In summary, the hypothesis that the presence of the Asp816Val mutation is linked to the occurrence of anaphylaxis was not supported, but interestingly, we have shown for the first time Asp816Val may occur more frequently than previously reported within the general population.
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Authors
Wendy Lawley, Heather Hird, Philip Mallinder, Sue McKenna, Beverley Hargadon, Alistair Murray, Peter Bradding,