Article ID Journal Published Year Pages File Type
9909132 Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2005 13 Pages PDF
Abstract
Following validation with known initiators, benzo(a)pyrene and N-methyl-N′-nitro-N-nitrosoguanidine and promoters, 12-O-tetradecanoyl-phorbol-13-acetate and phenobarbitone, the two-stage model was applied to cigarette smoke particulates which was found to act both at the initiation and promotion stage of cell transformation.
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Application of a two-stage Syrian hamster embryo cell transformation assay to cigarette smoke particulate matter
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