Article ID Journal Published Year Pages File Type
9910084 Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2005 8 Pages PDF
Abstract
CYP1A2 genetic polymorphisms are shown to influence the CYP1A2 phenotype in smokers, −2467 T → delT having the main effect. This information is of interest for future studies assessing the possible role of tobacco smoke-inducible CYP1A2 genotypes as individual susceptibility factors in exposure to carcinogens.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Preview
Influence of the genetic polymorphism in the 5′-noncoding region of the CYP1A2 gene on CYP1A2 phenotype and urinary mutagenicity in smokers
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