| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9912209 | Cytokine & Growth Factor Reviews | 2005 | 7 Pages |
Abstract
MicroRNAs (miRNA) are non-coding small (â¼22Â nt) RNAs that regulate diverse physiological and developmental processes. In animals, they regulate target genes by binding imperfectly to 3â²UTR sequences in mRNAs and attenuate translation. There are hundreds of miRNA genes in animals, and current studies show they constitute a minimum of 1% of known genes. We are just beginning to understand the diverse roles they play in cellular processes, which include signaling pathways, developmental pathways, and possibly various types of cancers.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Maocheng Yang, Ying Li, Richard W. Padgett,