Insulinémie et paramètres du syndrome métabolique dans une population de militaires français (étude EPIMIL)

The aim of EPIMIL, a prospective study involving 2045 military subjects (aged 20-58 years), is to investigate the relationships between markers of cardiovascular risk and components of the metabolic syndrome. We report here the first results concerning insulinemia in this population. The prevalence of metabolic syndrome was 9% according to the NCEP ATP III definition. Insulinemia was significantly higher (P < 0.001) in subjects with metabolic syndrome and growth regularly with the number of components of the metabolic syndrome. Insulinemia was significantly related to some clinical (age, blood pression) and biological markers (glycemia, haemoglobin A1C, total cholesterol, HDL- cholesterol (inverse correlation), microalbuminuria). Strong correlation were found between insulinemia and body mass index (r = 0.46; P < 0.0001), waist circumference (r = 0.45; P < 0.0001) and triglycerides (r = 0.36; P < 0.0001). Those markers are good indicators of hyperinsulinémia in patients with metabolic syndrome.