Antiphospholipid antibodies in pediatric patients with prolonged activated partial thromboplastin time during infection

During commonly acquired infections elevation of aPL of nearly all types seems to be a common process. Mild prolongation of aPTT might reflect this presence of aPL in the course of the infectious disease. Our data suggest that there exists no differences in specificity in comparison to the “pathogenic” aPL but the presence over time might be the trigger for the autoimmune activity to begin.