Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9914928 | Molecular and Cellular Endocrinology | 2005 | 9 Pages |
Abstract
Alendronate and pamidronate showed an inhibition of viability (â63 and â35%, respectively; p < 0.0001) and proliferation of cancer cells, while no effect was observed with clodronate. Amino-bisphosphonates induced a significant increase of apoptosis in MCF-7. In addition, they showed a significant decrease in telomerase expression and activity with respect to control and to clodronate.
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Authors
Luca Dalle Carbonare, Maria Teresa Valenti, Giuseppe Azzarello, Elena Balducci, Gaetano Crepaldi, Giuseppe Realdi, Orazio Vinante, Sandro Giannini,