Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9921072 | European Journal of Pharmacology | 2005 | 8 Pages |
Abstract
In conclusion, these data confirmed that (+)-cyclazosin is a selective α1B-adrenoceptor antagonist also in functional assays, showing 13- and 38-fold selectivity for the α1B-adrenoceptor over α1A- and α1D-subtypes, respectively. Furthermore, (+)-cyclazosin displayed a significant selectivity for α1B-adrenoceptors relative to the α1L-subtype.
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Authors
Gabriella Marucci, Piero Angeli, Michela Buccioni, Ugo Gulini, Carlo Melchiorre, Gianni Sagratini, Rodolfo Testa, Dario Giardinà ,