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Mechanisms underlying the inhibitory effects induced by pituitary adenylate cyclase-activating peptide in mouse ileum

Article ID Journal Published Year Pages File Type
9921098 European Journal of Pharmacology 2005 6 Pages PDF
Abstract
We suggest that, in mouse ileum, the inhibitory responses to PACAP-27 involve stimulation of PLC, increased production of IP3 and localised Ca2+ release from intracellular stores, which could provide the opening of apamin-sensitive Ca2+-dependent K+ channels.
Keywords
Inositol 1,4,5-triphosphateMouse ileumphospholipase C
Related Topics
Life Sciences Neuroscience Cellular and Molecular Neuroscience
Preview
Mechanisms underlying the inhibitory effects induced by pituitary adenylate cyclase-activating peptide in mouse ileum
Authors
Maria Grazia Zizzo, Flavia Mulè, Rosa Serio,
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Journal
European Journal of Pharmacology
Journal: European Journal of Pharmacology
Related Categories
Inositol 1,4,5-triphosphate
Mouse ileum
phospholipase C
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