Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9931746 | The Journal of Pain | 2005 | 11 Pages |
Abstract
Chronic inflammation during development can induce profound alterations in sensory processing later in life. Here we show that long-term inflammation initiated at critical developmental stages sensitizes both behavioral and neuronal responses to nociceptor stimulation in adulthood. An ongoing sensitization of the spinal cord is induced by the postnatal inflammatory insult.
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Authors
Andrea G. Hohmann, Mark H. Neely, Jeremiah Piña, Andrea G. Nackley,