Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9931820 | The Journal of Pain | 2005 | 5 Pages |
Abstract
This study shows that spinal nerve injury, but not peripheral inflammation, induces the expression of a chemokine, CX3CL1 (fractalkine), in astrocytes and upregulates CX3CR1 in microglia in the spinal cord. This selective regulation of CX3CL1 and its receptor, CX3CR1, suggests that these chemokines may represent new targets for the treatment of neuropathic pain.
Related Topics
Life Sciences
Neuroscience
Neurology
Authors
Jill A. Lindia, Erin McGowan, Nina Jochnowitz, Catherine Abbadie,