Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9933612 | International Journal of Developmental Neuroscience | 2005 | 7 Pages |
Abstract
These data suggest that immature cerebellar granule cells grown in vitro are highly vulnerable to ROS damage and that a therapeutic intervention could be effective in a narrow temporal window. Moreover, radiation-induced cell death can be partially prevented by a complete limitation of ROS generation, suggesting that other mechanisms besides oxidative stress would also be responsible for the cellular damage found in this model.
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Authors
Laura Ruth Guelman, Javier Ignacio Cabana, Romina MarÃa del Luján Pagotto, Luis MarÃa Zieher,