| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9945302 | The Annals of Thoracic Surgery | 2005 | 7 Pages |
Abstract
Pharmacologic inhibition of INO-1001 prolongs allograft survival in a dose-dependent fashion in a rodent model of heart transplantation. PARP inhibitors may permit reductions in the dose of CSA needed for adequate immunosuppression after heart transplantation.
Keywords
IVCNFATISHLTiNOSPARPACRADPAdenosine TriphosphateATPadenosine diphosphateInternational Society for Heart and Lung TransplantationCSAischemia-reperfusionanalysis of varianceANOVAParintraperitonealAcute cellular rejectioninducible nitric oxide synthaseCyclosporinePulmonary arteryNuclear Factor of Activated T CellsMHCmajor histocompatibility complexInferior vena cava
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Authors
Alexander S. MD, Anton S. MRCS, Brendan C. BS, Steven M. MRCS, Andrew D. PharmD, Min MD, PhD, Prakash PhD, Csaba MD, PhD, Christopher T. MD, PhD, Michael S. MD,