| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9954058 | Redox Biology | 2018 | 13 Pages |
Abstract
A novel mechanism depicting a role of S-sulfhydration in the regulation of CaMKII is presented. SPRC mediated S-sulfhydration of CaMKII was found to inhibit CAMKII activity and to preserve cardiovascular homeostasis.
Keywords
SPRCd,l-PropargylglycineH2Ss-SulfhydrationCSESERCA2aNaHSCaMKIIMPTPPLNPAGCa2+/calmodulin-dependent protein kinase IIcystathionine γ-lyaseHydrogen peroxidemitochondrial permeability transition poreISOIsoprenalineHydrogen sulfideSodium hydrogen sulfidephospholambanMitochondriaheart failureNitric oxideH2O2
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Authors
Dan Wu, Qingxun Hu, Bo Tan, Peter Rose, Deqiu Zhu, Yi Zhun Zhu,