Ability of gelatin and BSA to stabilize the supersaturated state of poorly soluble drugs

Article ID	Journal	Published Year	Pages	File Type
9954388	European Journal of Pharmaceutics and Biopharmaceutics	2018	50 Pages	PDF

Keywords

x¯CI95%PVPVA FaSSGF FeSSIF FaSSIF NMP API PVP LOQ DSC HPMC DMF supersaturation AUC BSA DMSO n-methyl pyrrolidone bovine serum albumin Bovine serum albumin (BSA)Solubility fasted state simulated intestinal fluid Fasted state simulated gastric fluid degrees of freedom GI-tract gastro intestinal tract fed state simulated Intestinal fluid dimethylformamide Dimethylsulfoxide BCs Biopolymers level of significance biopharmaceutics classification system Lod limit of quantification limit of detection Resistance area under the curve mean Active Pharmaceutical Ingredient ASD Hydroxypropyl methyl cellulose Protein Polypropylene Gelatin Differential scanning calorimetry

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology

Ability of gelatin and BSA to stabilize the supersaturated state of poorly soluble drugs

Authors

Timothy Pas, Alina Struyf, Bjorn Vergauwen, Guy Van den Mooter,