| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9954476 | Nuclear Medicine and Biology | 2018 | 35 Pages |
Abstract
A novel diphenyl sulfide derivative, [18F]1 for SERT imaging was successfully prepared and evaluated. Results suggest that this new chemical entity is targeting SERT binding sites in the brain, and it is a suitable candidate for future commercial development.
Keywords
DCMnorepinephrine transporterIPTDATDMFGBR12909MECNDASBTHFLLC-PK1BSADMSONisoxetineADAMbovine serum albuminEthylacetateAcetonitrileDopamine transporterSPECTTetrahydrofuransingle photon emission computed tomographyPositron emission tomographyNETdimethylformamideDichloromethaneDimethyl sulfoxideSERTserotonin transporterSelective serotonin reuptake inhibitorSSRIPET
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
![[18F]Diphenyl sulfide derivatives for imaging serotonin transporter (SERT) in the brain](/preview/png/9954476.png "First Page Preview: [18F]Diphenyl sulfide derivatives for imaging serotonin transporter (SERT) in the brain")
Authors
Yan Zhang, Futao Liu, Hao Xiao, Xinyue Yao, Genxun Li, Seok Rye Choi, Karl Ploessl, Zhihao Zha, Lin Zhu, Hank F. Kung,