| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9954477 | Nuclear Medicine and Biology | 2018 | 8 Pages |
Abstract
The addition of albumin binder motifs to [177Lu]Lu-DOTATATE enhanced mean residence time in blood. Increased tumour uptake was observed for [177Lu]Lu-AspAB-DOTATATE compared to [177Lu]Lu-DOTATATE at later time points, but its higher kidney uptake diminished the therapeutic index.
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![Effects of adding an albumin binder chain on [177Lu]Lu-DOTATATE](/preview/png/9954477.png "First Page Preview: Effects of adding an albumin binder chain on [177Lu]Lu-DOTATATE")
Authors
Etienne Rousseau, Joseph Lau, Zhengxing Zhang, Carlos F. Uribe, Hsiou-Ting Kuo, Chengcheng Zhang, Jutta Zeisler, Nadine Colpo, Kuo-Shyan Lin, François Bénard,