Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9955229 | Bone | 2018 | 40 Pages |
Abstract
Our study elucidated the potential benefits of HA-gelâ¯+â¯magnoflorine in promoting SCB regeneration and revealed a protective effect of stimulating recovery of the SCB integrity on attenuating cartilage degradation to prevent OA progression.
Keywords
ECMtrabecular bone pattern factorTGF-βSubchondral bone plateXTTTb.NTb.SpTb.ThSubchondral trabecular boneTRAPBMDTCMNF-κBROISBPBV/TVMAPKSCbOsteoarthritissubchondral boneOsteoclasttartrate-resistant acid phosphataseHyaluronic acidFractal dimensionTransforming Growth Factor Betaanalyses of varianceANOVAconnectivity densityBone mineral densitytrabecular separationDegree of anisotropytrabecular numbertrabecular thicknesstraditional Chinese medicineHyaline cartilageArticular cartilagecalcified cartilagenuclear factor kappa-light-chain-enhancer of activated B cellsExtracellular matrixregion of interestMagnoflorinepolymerase chain reactionPCRmitogen-activated protein kinaseBone volume fractionnegative control
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Authors
Zhe Cai, Yu Feng, Chentian Li, Kedi Yang, Tianhao Sun, Lei Xu, Yan Chen, Chun-Hoi Yan, William Weijia Lu, Kwong-Yuen Chiu,