| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9974918 | The Journal of Heart and Lung Transplantation | 2005 | 5 Pages |
Abstract
These data demonstrate that supplementation with the anti-oxidant agents vitamin C and vitamin E decreases CsA concentrations but does not appear to effect tacrolimus concentrations. Although more detailed pharmacokinetic analysis is necessary to clarify the exact mechanism of this interaction, physicians who take care of transplant recipients should be aware that more frequent CsA concentration monitoring is warranted after initiating these anti-oxidant agents.
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Authors
Kathleen D. PharmD, Keith D. MD, Laura E. RN, Francis D. MD, PhD, Todd M. MD,