| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9975098 | The Journal of Heart and Lung Transplantation | 2005 | 8 Pages |
Abstract
The results revealed surprising myocardial toxicity (enzymatic release) from components included in cardioplegic solutions. Some components would induce metabolic activation during prolonged hypothermic ischemia, which may be inappropriated and which may perhaps exacerbate damages by increasing membrane ruptures. This concept confirms eventual discrepant effects of preservative compounds on cardiomyocyte membrane during deep hypothermia, according to the metabolic state of the cell.
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
René PhD, Pierre PhD, Michel MD, PhD,