Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9975247 | The Journal of Heart and Lung Transplantation | 2005 | 7 Pages |
Abstract
This study further defines the effect of cyclosporine on GCAD in this cardiac transplantation model. In this system, higher dose and longer duration of treatment with CsA markedly reduces macrophage and MHC II infiltration, correlating with diminished GCAD. However, increasing dose and duration of CsA did not completely eliminate the development of GCAD. Non-immunologic factors could contribute to this occurrence.
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Authors
Maarten A. BS, David T. MD, Jasper M. BS, Murray H. MD, Seiichiro MD, PhD, Shannon H. BS, E.Grant Hoyt, Robert C. MD,