Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
9978599 | The Journal of Thoracic and Cardiovascular Surgery | 2005 | 9 Pages |
Abstract
Myoblast sheets repaired the impaired myocardium, reduced fibrosis, and prevented remodeling in association with recruitment of hematopoietic stem cells through the release of stromal-derived factor 1 and other growth factors. Our experiment indicates a therapy for patients with severe heart failure.
Keywords
RT-PCRSca-1stem cell antigen 1HGFCTXSDF-1HSC5′-bromo-2′-deoxyuridineBrdULeft ventricularanalysis of varianceANOVAMyosin heavy chainHematopoietic stem cellHepatocyte growth factorStromal-derived factor 1Vascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)LADMHCreverse transcription–polymerase chain reactionCell transplantationleft anterior descending coronary arteryejection fraction
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Authors
Imran A. MBBS, PhD, Yoshiki MD, PhD, Norihide MD, Goro MD, Shigeru MD, PhD, Satoshi MD, Satoru K. MD, PhD, Haruhiko MD, PhD, Alexey N. MD, PhD, Tatsuya MD, PhD, Teruo PhD, Hikaru MD,