| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9979209 | The Journal of Thoracic and Cardiovascular Surgery | 2005 | 5 Pages |
Abstract
Rolipram inhibited changes in adhesion molecule expression and interleukin-6 release by activated monocytes in simulated extracorporeal circulation. This study suggests that phosphodiesterase type 4 inhibition could be feasible therapeutic strategy to prevent exaggerated inflammatory response and organ injury in patients undergoing cardiopulmonary bypass.
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Authors
Yukio MD, PhD, Yuji MD, PhD, Satoshi MD, PhD, Makiko MD, Shyoko Sato, Shunsuke MD, PhD, Yasunori MD, PhD,