| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9979777 | The Journal of Thoracic and Cardiovascular Surgery | 2005 | 9 Pages |
Abstract
Human fetal cardiac myocytes exhibit a uniquely adaptive transcriptional response to ischemia and reperfusion that is associated with an apoptosis-resistant phenotype. The stress-inducible fetal cardiac myocyte gene repertoire is a useful platform for identification of targets relevant to the mitigation of cardiac ischemic injury and highlights a novel avenue involving interleukin 6 modulation for preventing the cardiac myocyte injury associated with ischemia and reperfusion.
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Authors
John G. MD, Cathy MSc, Mark PhD, Diane MSc, Astra Chang, Julia MD, Xiaojing MD, PhD, Changqing MD, Gabriel MSc, Hideaki MD, Jason PhD, Ashu Sunny MHSc, James PhD, Huanzhang PhD, Gregory PhD,