| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9980120 | The Journal of Thoracic and Cardiovascular Surgery | 2005 | 7 Pages |
Abstract
The unique findings of this study were 2-fold: First, significant compartmentalization of endothelin exists within the human myocardium. Second, a significantly higher and temporally disparate change in myocardial interstitial endothelin occurs during and after cardiopulmonary bypass when compared with systemic levels. These dynamic changes in myocardial endothelin likely influence coronary vascular tone and contractility.
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Authors
M. Marlina MS, John S. MD, PhD, Peter Y. MD, Elizabeth A. MD, Kim J. MD, Rupak PhD, B. Hugh MD, PhD, Francis G. MD, PhD,