| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9989601 | Neurobiology of Disease | 2005 | 11 Pages |
Abstract
Our data provide evidence that overexpression of mutated human A30P α-synuclein in mice leads to a reduced size of the dopamine storage pool. This is in agreement with the previously postulated involvement of α-synuclein in the turnover of transmitter vesicles and may explain the observed motor deficits in A30P mice.
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Authors
Leonid Yavich, Mari Oksman, Heikki Tanila, Petri Kerokoski, Mikko Hiltunen, Thomas van Groen, Jukka Puoliväli, Pekka T. Männistö, Arturo GarcÃa-Horsman, Ewen MacDonald, Konrad Beyreuther, Tobias Hartmann, Pekka Jäkälä,