Improving mitochondrial function significantly reduces metabolic, visual, motor and cognitive decline in aged Drosophila melanogaster Fulltext Access 39 Pages 2017
Optic atrophy 1 mediates coenzyme Q-responsive regulation of respiratory complex IV activity in brain mitochondria Fulltext Access 39 Pages 2017
n-3 Fatty acids, Mediterranean diet and cognitive function in normal aging: A systematic review Fulltext Access 39 Pages 2017
Bidirectional factors impact the migration of NK cells to draining lymph node in aged mice during influenza virus infection Fulltext Access 39 Pages 2017
Early hippocampal hyperexcitability in PS2APP mice: role of mutant PS2 and APP Fulltext Access 39 Pages 2017
A new function for the yeast trehalose-6P synthase (Tps1) protein, as key pro-survival factor during growth, chronological ageing, and apoptotic stress Fulltext Access 39 Pages 2017
Differential carbonylation of proteins in end-stage human fatty and nonfatty NASH Fulltext Access 40 Pages 2017
Specific patterns of spinal metabolites underlying α-Me-5-HT-evoked pruritus compared with histamine and capsaicin assessed by proton nuclear magnetic resonance spectroscopy Fulltext Access 40 Pages 2017
Worsening of memory deficit induced by energy-dense diet in a rat model of early-Alzheimer's disease is associated to neurotoxic Aβ species and independent of neuroinflammation Fulltext Access 40 Pages 2017
SOX2 function and Hedgehog signaling pathway are co-conspirators in promoting androgen independent prostate cancer Fulltext Access 40 Pages 2017
A single high dose of dexamethasone increases GAP-43 and synaptophysin in the hippocampus of aged rats Fulltext Access 40 Pages 2017
Intravenous treatment with human recombinant ApoA-I Milano reduces beta amyloid cerebral deposition in the APP23-transgenic mouse model of Alzheimer's disease Fulltext Access 40 Pages 2017
A novel redox regulator, MnTnBuOE-2-PyP5+, enhances normal hematopoietic stem/progenitor cell function Fulltext Access 40 Pages 2017
Characterization of a presymptomatic stage in a Drosophila Parkinson's disease model: Unveiling dopaminergic compensatory mechanisms Fulltext Access 40 Pages 2017
Autophagy regulates accumulation and functional activity of granulocytic myeloid-derived suppressor cells via STAT3 signaling in endotoxin shock Fulltext Access 40 Pages 2017
Regulatory role of NADPH oxidase 2 in the polarization dynamics and neurotoxicity of microglia/macrophages after traumatic brain injury Fulltext Access 40 Pages 2017
Tyr42 phosphorylation of RhoA GTPase promotes tumorigenesis through nuclear factor (NF)-κB Fulltext Access 40 Pages 2017
G6PD plays a neuroprotective role in brain ischemia through promoting pentose phosphate pathway Fulltext Access 40 Pages 2017
Serotonin disturbs colon epithelial tolerance of commensal E. coli by increasing NOX2-derived superoxide Fulltext Access 40 Pages 2017
The relevance of contact-independent cell-to-cell transfer of TDP-43 and SOD1 in amyotrophic lateral sclerosis Fulltext Access 40 Pages 2017
Systematic in vitro assessment of responses of roGFP2-based probes to physiologically relevant oxidant species Fulltext Access 40 Pages 2017
TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity Fulltext Access 40 Pages 2017
The NAD+-dependent deacetylase, Bifidobacterium longum Sir2 in response to oxidative stress by deacetylating SigH (ÏH) and FOXO3a in Bifidobacterium longum and HEK293T cell respectively Fulltext Access 40 Pages 2017
In vitro non-viral murine pro-neurotrophin 3 gene transfer into rat bone marrow stromal cells Fulltext Access 40 Pages 2017
BAG-1M co-activates BACE1 transcription through NF-κB and accelerates Aβ production and memory deficit in Alzheimer's disease mouse model Fulltext Access 40 Pages 2017
Changes in phagocytosis and potassium channel activity in microglia of 5xFAD mice indicate alterations in purinergic signaling in a mouse model of Alzheimer's disease Fulltext Access 40 Pages 2017
PGE2-EP3 signaling pathway impairs hippocampal presynaptic long-term plasticity in a mouse model of Alzheimer's disease Fulltext Access 40 Pages 2017
Oxidative stress, genomic features and DNA repair in frail elderly: A systematic review Fulltext Access 40 Pages 2017
MHC IIâ, but not MHC II+, hepatic Stellate cells contribute to liver fibrosis of mice in infection with Schistosoma japonicum Fulltext Access 40 Pages 2017
Control of the NADPH supply for oxidative stress handling in cancer cells Fulltext Access 41 Pages 2017
Conversion to carbidopa and levodopa extended-release (IPX066) followed by its extended use in patients previously taking controlled-release carbidopa-levodopa for advanced Parkinson's disease Fulltext Access 41 Pages 2017
Neurological disorders associated with DNA strand-break processing enzymes Fulltext Access 41 Pages 2017
Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation Fulltext Access 41 Pages 2017
CSF neurofilament light levels predict hippocampal atrophy in cognitively healthy older adults Fulltext Access 41 Pages 2017
Lysocardiolipin acyltransferase regulates TGF-β mediated lung fibroblast differentiation Fulltext Access 41 Pages 2017
The translocator protein ligand XBD173 improves clinical symptoms and neuropathological markers in the SJL/J mouse model of multiple sclerosis Fulltext Access 41 Pages 2017
3-NP-induced Huntington's-like disease impairs Nrf2 activation without loss of cardiac function in aged rats Fulltext Access 41 Pages 2017
The role of α-smooth muscle actin in fibroblast-mediated matrix contraction and remodeling Fulltext Access 41 Pages 2017
Reelin expression is up-regulated in mice colon in response to acute colitis and provides resistance against colitis Fulltext Access 41 Pages 2017
Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase Fulltext Access 41 Pages 2017
Wip1 directly dephosphorylates NLK and increases Wnt activity during germ cell development Fulltext Access 41 Pages 2017
Dihydromyricetin prevents obesity-induced slow-twitch-fiber reduction partially via FLCN/FNIP1/AMPK pathway Fulltext Access 41 Pages 2017
Role of microRNA in diabetic cardiomyopathy: From mechanism to intervention Fulltext Access 41 Pages 2017
Insulin increases filtration barrier permeability via TRPC6-dependent activation of PKGIα signaling pathways Fulltext Access 42 Pages 2017
Augmented O-GlcNAc signaling via glucosamine attenuates oxidative stress and apoptosis following contrast-induced acute kidney injury in rats Fulltext Access 42 Pages 2017
Prothrombin complex concentrate administration for bleeding associated with non-vitamin K antagonist oral anticoagulants: The SAMURAI-NVAF study Fulltext Access 42 Pages 2017
Physical interaction between the MAPK Slt2 of the PKC1-MAPK pathway and Grx3/Grx4 glutaredoxins is required for the oxidative stress response in budding yeast Fulltext Access 42 Pages 2017
Sustained blockade of ascorbic acid transport associated with marked SVCT1 loss in rat hepatocytes containing increased ascorbic acid levels after partial hepatectomy Fulltext Access 42 Pages 2017
The AtrbohF-dependent regulation of ROS signaling is required for melatonin-induced salinity tolerance in Arabidopsis Fulltext Access 42 Pages 2017
Hippocampal morphology and cognitive functions in community-dwelling older people: the Lothian Birth Cohort 1936 Fulltext Access 42 Pages 2017
Real-time quantification of subcellular H2O2 and glutathione redox potential in living cardiovascular tissues Fulltext Access 42 Pages 2017
Succinate accumulation impairs cardiac pyruvate dehydrogenase activity through GRP91-dependent and independent signaling pathways: Therapeutic effects of ginsenoside Rb1 Fulltext Access 42 Pages 2017
Time course of Tau toxicity and pharmacologic prevention in a cell model of Tauopathy Fulltext Access 42 Pages 2017
Chronicles of a reductase: Biochemistry, genetics and physio-pathological role of GSNOR Fulltext Access 42 Pages 2017
The emerging role of Wnt signaling dysregulation in the understanding and modification of age-associated diseases Fulltext Access 42 Pages 2017
Effects of vitamin D and resveratrol on metabolic associated markers in liver and adipose tissue from SAMP8 mice Fulltext Access 42 Pages 2017
Rac1 signaling regulates cigarette smoke-induced inflammation in the lung via the Erk1/2 MAPK and STAT3 pathways Fulltext Access 42 Pages 2017
Exosome-based immunomodulation during aging: A nano-perspective on inflamm-aging Fulltext Access 42 Pages 2017
UCP2 inhibition induces ROS/Akt/mTOR axis: Role of GAPDH nuclear translocation in genipin/everolimus anticancer synergism Fulltext Access 42 Pages 2017
Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds Fulltext Access 42 Pages 2017
ER-resident antioxidative GPx7 and GPx8 enzyme isoforms protect insulin-secreting INS-1E β-cells against lipotoxicity by improving the ER antioxidative capacity Fulltext Access 43 Pages 2017
Hotair facilitates hepatic stellate cells activation and fibrogenesis in the liver Fulltext Access 43 Pages 2017
Pomegranate peel extract attenuates D-galactose-induced oxidative stress and hearing loss by regulating PNUTS/PP1 activity in the mouse cochlea Fulltext Access 43 Pages 2017
RelB attenuates cigarette smoke extract-induced apoptosis in association with transcriptional regulation of the aryl hydrocarbon receptor Fulltext Access 43 Pages 2017
Redox regulation of the tumor suppressor PTEN by the thioredoxin system and cumene hydroperoxide Fulltext Access 43 Pages 2017
Klotho regulates postnatal neurogenesis and protects against age-related spatial memory loss Fulltext Access 43 Pages 2017
Cognitive reserve moderates the association between functional network anti-correlations and memory in MCI Fulltext Access 43 Pages 2017
Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations Fulltext Access 43 Pages 2017
Activation of brain glucose metabolism ameliorating cognitive impairment in APP/PS1 transgenic mice by electroacupuncture Fulltext Access 43 Pages 2017
Differential alteration of hippocampal function and plasticity in females and males of the APPxPS1 mouse model of Alzheimer's disease Fulltext Access 43 Pages 2017
P2X7 receptor promotes intestinal inflammation in chemically induced colitis and triggers death of mucosal regulatory T cells Fulltext Access 43 Pages 2017
Deletion of protein tyrosine phosphatase 1B obliterates endoplasmic reticulum stress-induced myocardial dysfunction through regulation of autophagy Fulltext Access 43 Pages 2017
A common polymorphism decreases LRP1 mRNA stability and is associated with increased plasma factor VIII levels Fulltext Access 44 Pages 2017
Changes in CD200 and intercellular adhesion molecule-1 (ICAM-1) levels in brains of Lewy body disorder cases are associated with amounts of Alzheimer's pathology not α-synuclein pathology Fulltext Access 44 Pages 2017
Berberine-induced cardioprotection and Sirt3 modulation in doxorubicin-treated H9c2 cardiomyoblasts Fulltext Access 44 Pages 2017
Sigma-1 receptor knockout increases α-synuclein aggregation and phosphorylation with loss of dopaminergic neurons in substantia nigra Fulltext Access 44 Pages 2017
Comparative effects of EtOH consumption and thiamine deficiency on cognitive impairment, oxidative damage, and β-amyloid peptide overproduction in the brain Fulltext Access 44 Pages 2017
Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc Fulltext Access 45 Pages 2017
Conserved effect of aging on DNA methylation and association with EZH2 polycomb protein in mice and humans Fulltext Access 45 Pages 2017
Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation Fulltext Access 45 Pages 2017
Redox regulation of cardiovascular inflammation - Immunomodulatory function of mitochondrial and Nox-derived reactive oxygen and nitrogen species Fulltext Access 45 Pages 2017
Mangiferin protects mitochondrial function by preserving mitochondrial hexokinase-II in vessel endothelial cells Fulltext Access 45 Pages 2017
Cerebral PET glucose hypometabolism in subjects with mild cognitive impairment and higher EEG high-alpha/low-alpha frequency power ratio Fulltext Access 46 Pages 2017
SERPINB1 ameliorates acute lung injury in liver transplantation through ERK1/2-mediated STAT3-dependent HO-1 induction Fulltext Access 46 Pages 2017
Biological impact of advanced glycation endproducts on estrogen receptor-positive MCF-7 breast cancer cells Fulltext Access 46 Pages 2017
Melatonin and nitric oxide regulate sunflower seedling growth under salt stress accompanying differential expression of Cu/Zn SOD and Mn SOD Fulltext Access 46 Pages 2017
Increased renal oxidative stress in salt-sensitive human GRK4γ486V transgenic mice Fulltext Access 46 Pages 2017
The telomere-binding protein TRF2 is required for metronomic therapeutic effects of gemcitabine and capecitabine Fulltext Access 46 Pages 2017
Nicotine slows down oligomerisation of α-synuclein and ameliorates cytotoxicity in a yeast model of Parkinson's disease Fulltext Access 46 Pages 2017
Parkin deficiency exacerbate ethanol-induced dopaminergic neurodegeneration by P38 pathway dependent inhibition of autophagy and mitochondrial function Fulltext Access 46 Pages 2017
Succinate-induced neuronal mitochondrial fission and hexokinase II malfunction in ischemic stroke: Therapeutical effects of kaempferol Fulltext Access 46 Pages 2017