A Western diet induced NAFLD in LDLRâ/â mice is associated with reduced hepatic glutathione synthesis Fulltext Access 9 Pages 2016
Bile acid receptor agonists INT747 and INT777 decrease oestrogen deficiency-related postmenopausal obesity and hepatic steatosis in mice Fulltext Access 9 Pages 2016
Resveratrol attenuates oxidative stress in mitochondrial Complex I deficiency: Involvement of SIRT3 Fulltext Access 9 Pages 2016
Influence of the APOE genotype on hepatic stress response: Studies in APOE targeted replacement mice and human liver cells Fulltext Access 9 Pages 2016
Protective effects of NSP-116, a novel imidazolyl aniline derivative, against light-induced retinal damage in vitro and in vivo Fulltext Access 9 Pages 2016
Protective effects of physical exercise on MDMA-induced cognitive and mitochondrial impairment Fulltext Access 9 Pages 2016
Lack of CHCHD2 mutations in Parkinson's disease in a Taiwanese population Fulltext Access 10 Pages 2016
Rosiglitazone activation of PPARγ-dependent pathways is neuroprotective in human neural stem cells against amyloid-beta-induced mitochondrial dysfunction and oxidative stress Fulltext Access 10 Pages 2016
Neuromelanin marks the spot: identifying a locus coeruleus biomarker of cognitive reserve in healthy aging Fulltext Access 10 Pages 2016
Survival strategies of elderly women in Ngangelizwe Township, Mthatha, South Africa: Livelihoods, social networks and income Fulltext Access 10 Pages 2016
CYP4F2 affects phenotypic outcome in adrenoleukodystrophy by modulating the clearance of very long-chain fatty acids Fulltext Access 10 Pages 2016
Metabolic signatures of Huntington's disease (HD): 1H NMR analysis of the polar metabolome in post-mortem human brain Fulltext Access 10 Pages 2016
Protein degradation in a LAMP-2-deficient B-lymphoblastoid cell line from a patient with Danon disease Fulltext Access 10 Pages 2016
Altered S-nitrosothiol homeostasis provides a survival advantage to breast cancer cells in HER2 tumors and reduces their sensitivity to trastuzumab Fulltext Access 10 Pages 2016
Enhanced Ccl2-Ccr2 signaling drives more severe choroidal neovascularization with aging Fulltext Access 10 Pages 2016
Risk-reducing Apolipoprotein E and Clusterin genotypes protect against the consequences of poor vascular health on executive function performance and change in nondemented older adults Fulltext Access 10 Pages 2016
Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging Fulltext Access 10 Pages 2016
VPS35 regulates cell surface recycling and signaling of dopamine receptor D1 Fulltext Access 10 Pages 2016
17β-estradiol replacement therapy protects myelin sheaths in the white matter of middle-aged female ovariectomized rats: a stereological study Fulltext Access 10 Pages 2016
Geriatric assessment in daily oncology practice for nurses and allied health care professionals: Opinion paper of the Nursing and Allied Health Interest Group of the International Society of Geriatric Oncology (SIOG) Fulltext Access 10 Pages 2016
Molecular hydrogen ameliorates several characteristics of preeclampsia in the Reduced Uterine Perfusion Pressure (RUPP) rat model Fulltext Access 10 Pages 2016
In situ visualization of carbonylation and its co-localization with proteins, lipids, DNA and RNA in Caenorhabditis elegans Fulltext Access 10 Pages 2016
The protection conferred against ischemia-reperfusion injury in the diabetic brain by N-acetylcysteine is associated with decreased dicarbonyl stress Fulltext Access 10 Pages 2016
Oxalomalate reduces expression and secretion of vascular endothelial growth factor in the retinal pigment epithelium and inhibits angiogenesis: Implications for age-related macular degeneration Fulltext Access 10 Pages 2016
The REVIVE (REal Women's VIews of Treatment Options for Menopausal Vaginal ChangEs) survey in Europe: Country-specific comparisons of postmenopausal women's perceptions, experiences and needs Fulltext Access 10 Pages 2016
The InterLACE study: Design, data harmonization and characteristics across 20 studies on women's health Fulltext Access 10 Pages 2016
Remote limb preconditioning protects against ischemia-induced neuronal death through ameliorating neuronal oxidative DNA damage and parthanatos Fulltext Access 10 Pages 2016
NS1619 regulates the expression of caveolin-1 protein in a time-dependent manner via ROS/PI3K/PKB/FoxO1 signaling pathway in brain tumor microvascular endothelial cells Fulltext Access 10 Pages 2016
Increasing tetrahydrobiopterin in cardiomyocytes adversely affects cardiac redox state and mitochondrial function independently of changes in NO production Fulltext Access 10 Pages 2016
Soluble receptor for advanced glycation end-products protects against ischemia/reperfusion-induced myocardial apoptosis via regulating the ubiquitin proteasome system Fulltext Access 10 Pages 2016
Mechanism of oxidative conversion of Amplex® Red to resorufin: Pulse radiolysis and enzymatic studies Fulltext Access 10 Pages 2016
Vitamin E metabolite 13â²-carboxychromanols inhibit pro-inflammatory enzymes, induce apoptosis and autophagy in human cancer cells by modulating sphingolipids and suppress colon tumor development in mice Fulltext Access 10 Pages 2016
AKAP-9 promotes colorectal cancer development by regulating Cdc42 interacting protein 4 Fulltext Access 10 Pages 2016
Artemisinin conferred ERK mediated neuroprotection to PC12 cells and cortical neurons exposed to sodium nitroprusside-induced oxidative insult Fulltext Access 10 Pages 2016
Low dose dietary nitrate improves endothelial dysfunction and plaque stability in the ApoEâ/â mouse fed a high fat diet Fulltext Access 10 Pages 2016
Inhibition of endoplasmic reticulum stress and oxidative stress by vitamin D in endothelial cells Fulltext Access 10 Pages 2016
Does p49/STRAP, a SRF-binding protein (SRFBP1), modulate cardiac mitochondrial function in aging? Fulltext Access 10 Pages 2016
Lysines, Achilles’ heel in alpha-synuclein conversion to a deadly neuronal endotoxin Fulltext Access 10 Pages 2016
Oral intake of genetically engineered high-carotenoid corn ameliorates hepatomegaly and hepatic steatosis in PTEN haploinsufficient mice Fulltext Access 10 Pages 2016
Reconstituted high-density lipoproteins acutely reduce soluble brain Aβ levels in symptomatic APP/PS1 mice Fulltext Access 10 Pages 2016
Homocysteine, hyperhomocysteinemia and vascular contributions to cognitive impairment and dementia (VCID) Fulltext Access 10 Pages 2016
Uncoupling protein 2 modulation of the NLRP3 inflammasome in astrocytes and its implications in depression Fulltext Access 10 Pages 2016
Distinctive adaptive response to repeated exposure to hydrogen peroxide associated with upregulation of DNA repair genes and cell cycle arrest Fulltext Access 10 Pages 2016
Dual NRF2 paralogs in Coho salmon and their antioxidant response element targets Fulltext Access 10 Pages 2016
Vam3 ameliorates total body irradiation-induced hematopoietic system injury partly by regulating the expression of Nrf2-targeted genes Fulltext Access 10 Pages 2016
The hydroxypyridinone iron chelator CP94 increases methyl-aminolevulinate-based photodynamic cell killing by increasing the generation of reactive oxygen species Fulltext Access 10 Pages 2016
Pleiotropic effects of 4-hydroxynonenal on oxidative burst and phagocytosis in neutrophils Fulltext Access 10 Pages 2016
Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration Fulltext Access 10 Pages 2016
Redox signaling in cardiovascular pathophysiology: A focus on hydrogen peroxide and vascular smooth muscle cells Fulltext Access 10 Pages 2016
C. elegans screening strategies to identify pro-longevity interventions Fulltext Access 10 Pages 2016
Association of falls with health-related quality of life (HRQOL) in older cancer survivors: A population based study Fulltext Access 10 Pages 2016
Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction Fulltext Access 10 Pages 2016
NADPH-cytochrome P450 reductase-mediated denitration reaction of 2,4,6-trinitrotoluene to yield nitrite in mammals Fulltext Access 10 Pages 2016
MicroRNA-2861 regulates programmed necrosis in cardiomyocyte by impairing adenine nucleotide translocase 1 expression Fulltext Access 10 Pages 2016
Ex vivo foam cell formation is enhanced in monocytes from older individuals by both extrinsic and intrinsic mechanisms Fulltext Access 10 Pages 2016
Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease Fulltext Access 10 Pages 2016
Dietary and donepezil modulation of mTOR signaling and neuroinflammation in the brain Fulltext Access 10 Pages 2016
GLI2 cell-specific activity is controlled at the level of transcription and RNA processing: Consequences to cancer metastasis Fulltext Access 10 Pages 2016
c-Abl links APP-BACE1 interaction promoting APP amyloidogenic processing in Niemann-Pick type C disease Fulltext Access 10 Pages 2016
The association of serum cathepsin B concentration with age-related cardiovascular-renal subclinical state in a healthy Chinese population Fulltext Access 10 Pages 2016
Lipidomics and H218O labeling techniques reveal increased remodeling of DHA-containing membrane phospholipids associated with abnormal locomotor responses in α-tocopherol deficient zebrafish (danio rerio) embryos Fulltext Access 10 Pages 2016
Yap1 and Skn7 genetically interact with Rad51 in response to oxidative stress and DNA double-strand break in Saccharomyces cerevisiae Fulltext Access 10 Pages 2016
Hypochlorite converts cysteinyl-dopamine into a cytotoxic product: A possible factor in Parkinson's Disease Fulltext Access 10 Pages 2016
4-Hydroxynonenal dependent alteration of TRPV1-mediated coronary microvascular signaling Fulltext Access 10 Pages 2016
Sex differences in angiotensin II responses contribute to a differential regulation of cox-mediated vascular dysfunction during aging Fulltext Access 10 Pages 2016
Cognitive and functional changes associated with Aβ pathology and the progression to mild cognitive impairment Fulltext Access 10 Pages 2016
Major amyloid-β-degrading enzymes, endothelin-converting enzyme-2 and neprilysin, are expressed by distinct populations of GABAergic interneurons in hippocampus and neocortex Fulltext Access 10 Pages 2016
Nrf2 silencing to inhibit proteolytic defense induced by hyperthermia in HT22 cells Fulltext Access 10 Pages 2016
The methyl donor S-adenosylmethionine prevents liver hypoxia and dysregulation of mitochondrial bioenergetic function in a rat model of alcohol-induced fatty liver disease Fulltext Access 10 Pages 2016
Fatty acid nitroalkenes induce resistance to ischemic cardiac injury by modulating mitochondrial respiration at complex II Fulltext Access 10 Pages 2016
Oxidative stress-induced premature senescence dysregulates VEGF and CFH expression in retinal pigment epithelial cells: Implications for Age-related Macular Degeneration Fulltext Access 10 Pages 2016
The anthocyanin cyanidin-3-O-β-glucoside modulates murine glutathione homeostasis in a manner dependent on genetic background Fulltext Access 10 Pages 2016
Deletion of GSTA4-4 results in increased mitochondrial post-translational modification of proteins by reactive aldehydes following chronic ethanol consumption in mice Fulltext Access 10 Pages 2016
Reproductive potential and instability of the rDNA region of the Saccharomyces cerevisiae yeast: Common or separate mechanisms of regulation? Fulltext Access 11 Pages 2016
Signaling pathways involved in HSP32 induction by hyperbaric oxygen in rat spinal neurons Fulltext Access 11 Pages 2016
Advanced oxidation protein products sensitized the transient receptor potential vanilloid 1 via NADPH oxidase 1 and 4 to cause mechanical hyperalgesia Fulltext Access 11 Pages 2016
Age-associated changes in DNA methylation across multiple tissues in an inbred mouse model Fulltext Access 11 Pages 2016
Disrupted dynamics of F-actin and insulin granule fusion in INS-1 832/13 beta-cells exposed to glucotoxicity: partial restoration by glucagon-like peptide 1 Fulltext Access 11 Pages 2016
Aberrant hippocampal Atp8a1 levels are associated with altered synaptic strength, electrical activity, and autistic-like behavior Fulltext Access 11 Pages 2016
Sex-determining region Y-box 9 acts downstream of NADPH oxidase to influence the effect of leptin on PPARγ1 expression in hepatic stellate cells Fulltext Access 11 Pages 2016
Cardiac ubiquitin ligases: Their role in cardiac metabolism, autophagy, cardioprotection and therapeutic potential Fulltext Access 11 Pages 2016
Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects Fulltext Access 11 Pages 2016
Moderately lower temperatures greatly extend the lifespan of Brachionus manjavacas (Rotifera): Thermodynamics or gene regulation? Fulltext Access 11 Pages 2016
Aging-related 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurochemial and behavioral deficits and redox dysfunction: improvement by AK-7 Fulltext Access 11 Pages 2016
The lncRNA MALAT1, acting through HIF-1α stabilization, enhances arsenite-induced glycolysis in human hepatic L-02 cells Fulltext Access 11 Pages 2016
Cross-talk between two antioxidants, thioredoxin reductase and heme oxygenase-1, and therapeutic implications for multiple myeloma Fulltext Access 11 Pages 2016
Early-onset motor impairment and increased accumulation of phosphorylated α-synuclein in the motor cortex of normal aging mice are ameliorated by coenzyme Q Fulltext Access 11 Pages 2016
Prominent role of exopeptidase DPP III in estrogen-mediated protection against hyperoxia in vivo Fulltext Access 11 Pages 2016
Deficits in coordinated motor behavior and in nigrostriatal dopaminergic system ameliorated and VMAT2 expression up-regulated in aged male rats by administration of testosterone propionate Fulltext Access 11 Pages 2016
Novel effects of sphingosylphosphorylcholine on invasion of breast cancer: Involvement of matrix metalloproteinase-3 secretion leading to WNT activation Fulltext Access 11 Pages 2016