State- and trait-dependent associations of vitamin-D with brain function during aging Fulltext Access 30 Pages 2016
The chemical biology of the persulfide (RSSH)/perthiyl (RSS·) redox couple and possible role in biological redox signaling Fulltext Access 30 Pages 2016
DDAH1 deficiency promotes intracellular oxidative stress and cell apoptosis via a miR-21-dependent pathway in mouse embryonic fibroblasts Fulltext Access 30 Pages 2016
Linking CSF and cognition in Alzheimer's disease: Reanalysis of clinical data Fulltext Access 31 Pages 2016
Braak staging, plaque pathology, and APOE status in elderly persons without cognitive impairment Fulltext Access 31 Pages 2016
BMP-9 enhances fibroblast growth factor 21 expression and suppresses obesity Fulltext Access 31 Pages 2016
Deposition of amyloid β in the walls of human leptomeningeal arteries in relation to perivascular drainage pathways in cerebral amyloid angiopathy Fulltext Access 31 Pages 2016
APOE and aging-related cognitive change in a longitudinal cohort of men Fulltext Access 31 Pages 2016
Enhanced resting-state functional connectivity between core memory-task activation peaks is associated with memory impairment in MCI Fulltext Access 31 Pages 2016
The PSSMAR study. Postacute sarcopenia: Supplementation with β-hydroxyMethylbutyrate after resistance training: Study protocol of a randomized, double-blind controlled trial Fulltext Access 31 Pages 2016
An attenuated immune response by Schwann cells and macrophages inhibits nerve regeneration in aged rats Fulltext Access 31 Pages 2016
A new perspective of the structural complexity of HCMV-specific T-cell responses Fulltext Access 31 Pages 2016
Hyperketonemia and ketosis increase the risk of complications in type 1 diabetes Fulltext Access 31 Pages 2016
MnTE-2-PyP reduces prostate cancer growth and metastasis by suppressing p300 activity and p300/HIF-1/CREB binding to the promoter region of the PAI-1 gene Fulltext Access 31 Pages 2016
Redox proteomic profiling of neuroketal-adducted proteins in human brain: Regional vulnerability at middle age increases in the elderly Fulltext Access 31 Pages 2016
Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage Fulltext Access 31 Pages 2016
PGC-1α overexpression via local transfection attenuates mitophagy pathway in muscle disuse atrophy Fulltext Access 31 Pages 2016
Impact of weight loss induced by gastric bypass or caloric restriction on oxidative stress and genomic damage in obese Zucker rats Fulltext Access 32 Pages 2016
Advances in the development of tau PET radiotracers and their clinical applications Fulltext Access 32 Pages 2016
Common variants in ABCA7 and MS4A6A are associated with cortical and hippocampal atrophy Fulltext Access 32 Pages 2016
Cytochrome P450 and matrix metalloproteinase genetic modifiers of disease severity in Cerebral Cavernous Malformation type 1 Fulltext Access 32 Pages 2016
Oxidized LDL induced extracellular trap formation in human neutrophils via TLR-PKC-IRAK-MAPK and NADPH-oxidase activation Fulltext Access 32 Pages 2016
MKK3 influences mitophagy and is involved in cigarette smoke-induced inflammation Fulltext Access 32 Pages 2016
Effect of the pituitary adenylate cyclase-activating polypeptide on the autophagic activation observed in in vitro and in vivo models of Parkinson's disease Fulltext Access 32 Pages 2016
Melatonin alleviates hyperthyroidism induced oxidative stress and neuronal cell death in hippocampus of aged female golden hamster, Mesocricetus auratus Fulltext Access 32 Pages 2016
High homocysteine and epistasis between MTHFR and APOE: association with cognitive performance in the elderly Fulltext Access 32 Pages 2016
Association between shift work history and performance on the trail making test in middle-aged and elderly humans: the EpiHealth study Fulltext Access 32 Pages 2016
The role of mitochondrial DNA damage in the development of atherosclerosis Fulltext Access 32 Pages 2016
Effect of the SOD mimetic MnL4 on in vitro and in vivo oxaliplatin toxicity: Possible aid in chemotherapy induced neuropathy Fulltext Access 32 Pages 2016
Luteolin inhibits viral-induced inflammatory response in RAW264.7 cells via suppression of STAT1/3 dependent NF-κB and activation of HO-1 Fulltext Access 33 Pages 2016
Platinum anti-cancer drugs: Free radical mechanism of Pt-DNA adduct formation and anti-neoplastic effect Fulltext Access 33 Pages 2016
ZYZ451 protects cardiomyocytes from hypoxia-induced apoptosis via enhancing MnSOD and STAT3 interaction Fulltext Access 33 Pages 2016
Potentially diagnostic electron paramagnetic resonance spectra elucidate the underlying mechanism of mitochondrial dysfunction in the deoxyguanosine kinase deficient rat model of a genetic mitochondrial DNA depletion syndrome Fulltext Access 33 Pages 2016
Validation of Thwaites Index for diagnosing tuberculous meningitis in a Colombian population Fulltext Access 33 Pages 2016
Familial longevity study reveals a significant association of mitochondrial DNA copy number between centenarians and their offspring Fulltext Access 33 Pages 2016
Hippocampal network dynamics in response to α7 nACh receptors activation in amyloid-β overproducing transgenic mice Fulltext Access 33 Pages 2016
Differential effects of amyloid-beta 1-40 and 1-42 fibrils on 5-HT1A serotonin receptors in rat brain Fulltext Access 33 Pages 2016
Cells redox environment modulates BRCA1 expression and DNA homologous recombination repair Fulltext Access 34 Pages 2016
Reproductive aging is associated with changes in oocyte mitochondrial dynamics, function, and mtDNA quantity Fulltext Access 34 Pages 2016
Reversible oxidation controls the activity and oligomeric state of the mammalian phosphoglycolate phosphatase AUM Fulltext Access 34 Pages 2016
Cigarette smoke extract (CSE) induces transient receptor potential ankyrin 1(TRPA1) expression via activation of HIF1αin A549 cells Fulltext Access 34 Pages 2016
Overexpression of HDAC6 induces pro-inflammatory responses by regulating ROS-MAPK-NF-κB/AP-1 signaling pathways in macrophages Fulltext Access 34 Pages 2016
Mitochondrial response to the BCKDK-deficiency: Some clues to understand the positive dietary response in this form of autism Fulltext Access 34 Pages 2016
Downregulation of miR-205 in migrating epithelial tongue facilitates skin wound re-epithelialization by derepressing ITGA5 Fulltext Access 34 Pages 2016
“What makes some rats live so long?” The mitochondrial contribution to longevity through balance of mitochondrial dynamics and mtDNA content Fulltext Access 34 Pages 2016
Evaluation of in vivo mitochondrial bioenergetics in skeletal muscle using NMR and optical methods Fulltext Access 35 Pages 2016
Pre-treatment of rats with ad-hepcidin prevents iron-induced oxidative stress in the brain Fulltext Access 35 Pages 2016
The antioxidant transcription factor Nrf2 contributes to the protective effect of mild thermotolerance (40 °C) against heat shock-induced apoptosis Fulltext Access 35 Pages 2016
Sulforaphane exerts its anti-inflammatory effect against amyloid-β peptide via STAT-1 dephosphorylation and activation of Nrf2/HO-1 cascade in human THP-1 macrophages Fulltext Access 35 Pages 2016
Functional thioredoxin reductase from pathogenic and free-living Leptospira spp. Fulltext Access 35 Pages 2016
Sleep as spatiotemporal integration of biological processes that evolved to periodically reinforce neurodynamic and metabolic homeostasis: The 2m3d paradigm of sleep Fulltext Access 35 Pages 2016
Structural equation modeling identifies markers of damage and function in the aging male Fischer 344 rat Fulltext Access 35 Pages 2016
NADPH oxidase 4 deficiency leads to impaired wound repair and reduced dityrosine-crosslinking, but does not affect myofibroblast formation Fulltext Access 35 Pages 2016
Meta-analysis of apolipoprotein E levels in the cerebrospinal fluid of patients with Alzheimer's disease Fulltext Access 35 Pages 2016
Persister formation in Escherichia coli can be inhibited by treatment with nitric oxide Fulltext Access 35 Pages 2016
Impact of a switch to fingolimod on depressive symptoms in patients with relapsing multiple sclerosis: An analysis from the EPOC (Evaluate Patient OutComes) trial Fulltext Access 35 Pages 2016
Evidence for synergistic action of transthyretin and IGF-I over the IGF-I receptor Fulltext Access 35 Pages 2016
NFκBiz protein downregulation in acute kidney injury: Modulation of inflammation and survival in tubular cells Fulltext Access 35 Pages 2016
Resveratrol attenuates monocyte-to-macrophage differentiation and associated inflammation via modulation of intracellular GSH homeostasis: Relevance in atherosclerosis Fulltext Access 36 Pages 2016
Intracellular labile iron determines H2O2-induced apoptotic signaling via sustained activation of ASK1/JNK-p38 axis Fulltext Access 36 Pages 2016
Simultaneous activation of Nrf2 and elevation of antioxidant compounds for reducing oxidative stress and chronic inflammation in human Alzheimer's disease Fulltext Access 36 Pages 2016
Upregulation of microRNA-22 contributes to myocardial ischemia-reperfusion injury by interfering with the mitochondrial function Fulltext Access 36 Pages 2016
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA Fulltext Access 36 Pages 2016
Large C9orf72 repeat expansions are seen in Chinese patients with sporadic amyotrophic lateral sclerosis Fulltext Access 36 Pages 2016
PPAR-pan activation induces hepatic oxidative stress and lipidomic remodelling Fulltext Access 36 Pages 2016
Mitophagy receptors sense stress signals and couple mitochondrial dynamic machinery for mitochondrial quality control Fulltext Access 36 Pages 2016
The relationship between nutrition and frailty: Effects of protein intake, nutritional supplementation, vitamin D and exercise on muscle metabolism in the elderly. A systematic review Fulltext Access 36 Pages 2016
Up-regulation of Nrf2 is involved in FGF21-mediated fenofibrate protection against type 1 diabetic nephropathy Fulltext Access 36 Pages 2016
Lynx1 and Aβ1-42 bind competitively to multiple nicotinic acetylcholine receptor subtypes Fulltext Access 36 Pages 2016
Brain volume changes in gait control in patients with mild cognitive impairment compared to cognitively healthy individuals; GAIT study results Fulltext Access 36 Pages 2016
Effects of caloric restriction on O-GlcNAcylation, Ca2+ signaling, and learning impairment in the hippocampus of ob/ob mice Fulltext Access 36 Pages 2016
Age-associated differences on structural brain MRI in nondemented individuals from 71 to 103 years Fulltext Access 36 Pages 2016
Dopamine modulation of spatial navigation memory in Parkinson's disease Fulltext Access 36 Pages 2016
S-propargyl-cysteine attenuates inflammatory response in rheumatoid arthritis by modulating the Nrf2-ARE signaling pathway Fulltext Access 37 Pages 2016
Glucagon-like peptide-1 improves beta-cell antioxidant capacity via extracellular regulated kinases pathway and Nrf2 translocation Fulltext Access 37 Pages 2016
A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain Fulltext Access 37 Pages 2016
Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms Fulltext Access 37 Pages 2016
Distribution of human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) in canines after intracerebroventricular injection Fulltext Access 37 Pages 2016
Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation Fulltext Access 37 Pages 2016
Association of genetic risk factors with cognitive decline: the PATH through life project Fulltext Access 37 Pages 2016
Measuring frailty in Dutch community-dwelling older people: Reference values of the Tilburg Frailty Indicator (TFI) Fulltext Access 37 Pages 2016
Angiotensin II type-2 receptor stimulation induces neuronal VEGF synthesis after cerebral ischemia Fulltext Access 37 Pages 2016
miR-322 regulates insulin signaling pathway and protects against metabolic syndrome-induced cardiac dysfunction in mice Fulltext Access 37 Pages 2016
GSH-targeted nanosponges increase doxorubicin-induced toxicity “in vitro” and “in vivo” in cancer cells with high antioxidant defenses Fulltext Access 37 Pages 2016
9-Norbornyl-6-chloropurine (NCP) induces cell death through GSH depletion-associated ER stress and mitochondrial dysfunction Fulltext Access 37 Pages 2016
Hydrogen peroxide mediated mitochondrial UNG1-PRDX3 interaction and UNG1 degradation Fulltext Access 38 Pages 2016
A role for β2* nicotinic receptors in a model of local amyloid pathology induced in dentate gyrus Fulltext Access 38 Pages 2016
Simultaneous quantitation of oxidized and reduced glutathione via LC-MS/MS: An insight into the redox state of hematopoietic stem cells Fulltext Access 38 Pages 2016
A SIRT3/AMPK/autophagy network orchestrates the protective effects of trans-resveratrol in stressed peritoneal macrophages and RAW 264.7 macrophages Fulltext Access 38 Pages 2016
The influence of the amyloid Ã-protein and its precursor in modulating cerebral hemostasis Fulltext Access 39 Pages 2016
Withanolide A offers neuroprotection, ameliorates stress resistance and prolongs the life expectancy of Caenorhabditis elegans Fulltext Access 39 Pages 2016