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Daneshyari Ageing Journas Latest Articles

Ageing Research Articles

The effect of amyloid-β peptide on synaptic plasticity and memory is influenced by different isoforms, concentrations, and aggregation status
Fulltext Access 37 Pages 2018
Sirtuin 3-induced macrophage autophagy in regulating NLRP3 inflammasome activation
Fulltext Access 37 Pages 2018
Cancer-associated fibroblasts promote epithelial-mesenchymal transition and EGFR-TKI resistance of non-small cell lung cancers via HGF/IGF-1/ANXA2 signaling
Fulltext Access 37 Pages 2018
Musashi-1 promotes chemoresistant granule formation by PKR/eIF2α signalling cascade in refractory glioblastoma
Fulltext Access 37 Pages 2018
Klotho protects the heart from hyperglycemia-induced injury by inactivating ROS and NF-κB-mediated inflammation both in vitro and in vivo
Fulltext Access 37 Pages 2018
Succinate induces synovial angiogenesis in rheumatoid arthritis through metabolic remodeling and HIF-1α/VEGF axis
Fulltext Access 37 Pages 2018
4-PBA ameliorates cellular homeostasis in fibroblasts from osteogenesis imperfecta patients by enhancing autophagy and stimulating protein secretion
Fulltext Access 37 Pages 2018
A multi-omics analysis of the regulatory changes induced by miR-223 in a monocyte/macrophage cell line
Fulltext Access 37 Pages 2018
An evolving understanding of the S-glutathionylation cycle in pathways of redox regulation
Fulltext Access 37 Pages 2018
Anagliptin inhibits neointimal hyperplasia after balloon injury via endothelial cell-specific modulation of SOD-1/RhoA/JNK signaling in the arterial wall
Fulltext Access 37 Pages 2018
C1QTNF1 attenuates angiotensin II-induced cardiac hypertrophy via activation of the AMPKa pathway
Fulltext Access 37 Pages 2018
Sirtuins in mitochondrial stress: Indispensable helpers behind the scenes
Fulltext Access 37 Pages 2018
Effect of heterochromatin stability on intestinal stem cell aging in Drosophila
Fulltext Access 37 Pages 2018
Metformin selectively targets redox control of complex I energy transduction
Fulltext Access 37 Pages 2018
Sex- and age-specific modulation of brain GABA levels in a mouse model of Alzheimer's disease
Fulltext Access 37 Pages 2018
Myocardin-related transcription factor A (MRTF-A) contributes to acute kidney injury by regulating macrophage ROS production
Fulltext Access 37 Pages 2018
An APOE-independent cis-eSNP on chromosome 19q13.32 influences tau levels and late-onset Alzheimer's disease risk
Fulltext Access 37 Pages 2018
ALK3 undergoes ligand-independent homodimerization and BMP-induced heterodimerization with ALK2
Fulltext Access 37 Pages 2018
Selenium, selenoprotein P, and Alzheimer's disease: is there a link?
Fulltext Access 37 Pages 2018
Non-tumor adjacent tissue of advanced stage from CRC shows activated antioxidant response
Fulltext Access 37 Pages 2018
“Lipid raft aging” in the human frontal cortex during nonpathological aging: gender influences and potential implications in Alzheimer's disease
Fulltext Access 37 Pages 2018
Polycystin-1 downregulation induces ERK-dependent mTOR pathway activation in a cellular model of psoriasis
Fulltext Access 37 Pages 2018
GCN2 deficiency protects against high fat diet induced hepatic steatosis and insulin resistance in mice
Fulltext Access 37 Pages 2018
Cerebral microhemorrhages due to traumatic brain injury and their effects on the aging human brain
Fulltext Access 37 Pages 2018
The FBN rat model of aging: investigation of ABR waveforms and ribbon synapse changes
Fulltext Access 37 Pages 2018
Honokiol alleviates the degeneration of intervertebral disc via suppressing the activation of TXNIP-NLRP3 inflammasome signal pathway
Fulltext Access 38 Pages 2018
Activation of the monocytic α7 nicotinic acetylcholine receptor modulates oxidative stress and inflammation-associated development of coronary artery spasm via a p38 MAP-kinase signaling-dependent pathway
Fulltext Access 38 Pages 2018
Missense mutation of SPAST protein (I344K) results in loss of ATPase activity and prolonged the half-life, implicated in autosomal dominant hereditary spastic paraplegia
Fulltext Access 38 Pages 2018
Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis
Fulltext Access 38 Pages 2018
Ripk3 promotes ER stress-induced necroptosis in cardiac IR injury: A mechanism involving calcium overload/XO/ROS/mPTP pathway
Fulltext Access 38 Pages 2018
Paradoxical effects of mutant ubiquitin on Aβ plaque formation in an Alzheimer mouse model
Fulltext Access 38 Pages 2018
Apigenin C-glycosides of Microcos paniculata protects lipopolysaccharide induced apoptosis and inflammation in acute lung injury through TLR4 signaling pathway
Fulltext Access 38 Pages 2018
Autophagy and oxidative stress in non-communicable diseases: A matter of the inflammatory state?
Fulltext Access 38 Pages 2018
Promastigote parasites cultured from the lesions of patients with mucosal leishmaniasis are more resistant to oxidative stress than promastigotes from a cutaneous lesion
Fulltext Access 38 Pages 2018
NADPH oxidase, oxidative stress and fibrosis in systemic sclerosis
Fulltext Access 38 Pages 2018
Frequency of C9orf72 hexanucleotide repeat expansion and SOD1 mutations in Portuguese patients with amyotrophic lateral sclerosis
Fulltext Access 38 Pages 2018
Histone methyltransferase G9a modulates hepatic insulin signaling via regulating HMGA1
Fulltext Access 38 Pages 2018
Early disruption of parvalbumin expression and perineuronal nets in the hippocampus of the Tg2576 mouse model of Alzheimer's disease can be rescued by enriched environment
Fulltext Access 38 Pages 2018
Activation of bradykinin B2 receptor induced the inflammatory responses of cytosolic phospholipase A2 after the early traumatic brain injury
Fulltext Access 38 Pages 2018
YAP promotes breast cancer metastasis by repressing growth differentiation factor-15
Fulltext Access 38 Pages 2018
The neurochemistry of agitation in Alzheimer's disease: a systematic review
Fulltext Access 39 Pages 2018
Neurofilament relates to white matter microstructure in older adults
Fulltext Access 39 Pages 2018
Epigenetic dysregulation of ZEB1 is involved in LMO2-promoted T-cell acute lymphoblastic leukaemia leukaemogenesis
Fulltext Access 39 Pages 2018
Nrf2 inhibits oxaliplatin-induced peripheral neuropathy via protection of mitochondrial function
Fulltext Access 39 Pages 2018
Reduction of nitrosative stress by methane: Neuroprotection through xanthine oxidoreductase inhibition in a rat model of mesenteric ischemia-reperfusion
Fulltext Access 39 Pages 2018
MicroRNAs to differentiate Parkinsonian disorders: Advances in biomarkers and therapeutics
Fulltext Access 39 Pages 2018
Fibronectin induces the perivascular deposition of cerebrospinal fluid-derived amyloid-β in aging and after stroke
Fulltext Access 39 Pages 2018
Hepatocyte-specific deletion of LASS2 protects against diet-induced hepatic steatosis and insulin resistance
Fulltext Access 39 Pages 2018
TRPM2 mediates mitochondria-dependent apoptosis of melanocytes under oxidative stress
Fulltext Access 39 Pages 2018
Reduced substantia innominata volume mediates contributions of microvascular and macrovascular disease to cognitive deficits in Alzheimer's disease
Fulltext Access 39 Pages 2018
Predominant subcortical accumulation of 18F-flortaucipir binding in behavioral variant frontotemporal dementia
Fulltext Access 39 Pages 2018
DAPK1-ERK signal mediates oxygen glucose deprivation reperfusion induced apoptosis in mouse N2a cells
Fulltext Access 39 Pages 2018
Proteome oxidative carbonylation during oxidative stress-induced premature senescence of WI-38 human fibroblasts
Fulltext Access 39 Pages 2018
Phenotype variability and allelic heterogeneity in KMT2B-Associated disease
Fulltext Access 39 Pages 2018
Nrf2 expression and function, but not MT expression, is indispensable for sulforaphane-mediated protection against intermittent hypoxia-induced cardiomyopathy in mice
Fulltext Access 39 Pages 2018
Herpud1 impacts insulin-dependent glucose uptake in skeletal muscle cells by controlling the Ca2+-calcineurin-Akt axis
Fulltext Access 39 Pages 2018
Utrophin up-regulation by artificial transcription factors induces muscle rescue and impacts the neuromuscular junction in mdx mice
Fulltext Access 39 Pages 2018
Effects of aging on executive functioning and mesocorticolimbic dopamine markers in male Fischer 344 × brown Norway rats
Fulltext Access 39 Pages 2018
Effects of APOE ε4 on neuroimaging, cerebrospinal fluid biomarkers, and cognition in prodromal Alzheimer's disease
Fulltext Access 39 Pages 2018
Dysregulated Txnip-ROS-Wnt axis contributes to the impaired ischemic heart repair in diabetic mice
Fulltext Access 39 Pages 2018
LAURDAN fluorescence and phasor plots reveal the effects of a H2O2 bolus in NIH-3T3 fibroblast membranes dynamics and hydration
Fulltext Access 39 Pages 2018
UVA-induced carbon-centred radicals in lightly pigmented cells detected using ESR spectroscopy
Fulltext Access 39 Pages 2018
Nesfatin-1 functions as a switch for phenotype transformation and proliferation of VSMCs in hypertensive vascular remodeling
Fulltext Access 39 Pages 2018
Development of a novel monoclonal antibody against 4-hydroxy-2E,6Z-dodecadienal (4-HDDE)-protein adducts: Immunochemical application in quantitative and qualitative analyses of lipid peroxidation in vitro and ex vivo
Fulltext Access 39 Pages 2018
Genetically reducing mTOR signaling rescues central insulin dysregulation in a mouse model of Alzheimer's disease
Fulltext Access 39 Pages 2018
Cannabidiol induced apoptosis in human monocytes through mitochondrial permeability transition pore-mediated ROS production
Fulltext Access 39 Pages 2018
ROS modifiers and NOX4 affect the expression of the survivin-associated radio-adaptive response
Fulltext Access 39 Pages 2018
Curvilinear locus coeruleus functional connectivity trajectories over the adult lifespan: a 7T MRI study
Fulltext Access 39 Pages 2018
PGE2 induces apoptosis of hepatic stellate cells and attenuates liver fibrosis in mice by downregulating miR-23a-5p and miR-28a-5p
Fulltext Access 40 Pages 2018
The proinflammatory effects of macrophage-derived NADPH oxidase function in autoimmune diabetes
Fulltext Access 40 Pages 2018
Reduced levels of methyltransferase DNMT2 sensitize human fibroblasts to oxidative stress and DNA damage that is accompanied by changes in proliferation-related miRNA expression
Fulltext Access 40 Pages 2018
Role of hypochlorous acid (HOCl) and other inflammatory mediators in the induction of macrophage extracellular trap formation
Fulltext Access 40 Pages 2018
Splenectomy protects aged mice from injury after experimental stroke
Fulltext Access 40 Pages 2018
Atypical PKC, PKCλ/ι, activates β-secretase and increases Aβ1-40/42 and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormalities in Alzheime
Fulltext Access 40 Pages 2018
Exosomal biomarkers in Down syndrome and Alzheimer's disease
Fulltext Access 40 Pages 2018
Cholemic nephropathy - Historical notes and novel perspectives
Fulltext Access 40 Pages 2018
Reactive oxygen species released from astrocytes treated with amyloid beta oligomers elicit neuronal calcium signals that decrease phospho-Ser727-STAT3 nuclear content
Fulltext Access 40 Pages 2018
Disruption of AT-hook 1 domain in MeCP2 protein caused behavioral abnormality in mice
Fulltext Access 40 Pages 2018
Melatonin protects diabetic heart against ischemia-reperfusion injury, role of membrane receptor-dependent cGMP-PKG activation
Fulltext Access 40 Pages 2018
Borago officinalis L. attenuates UVB-induced skin photodamage via regulation of AP-1 and Nrf2/ARE pathway in normal human dermal fibroblasts and promotion of collagen synthesis in hairless mice
Fulltext Access 40 Pages 2018
19q13.12 microdeletion syndrome fibroblasts display abnormal storage of cholesterol and sphingolipids in the endo-lysosomal system
Fulltext Access 40 Pages 2018
A high-sensitivity electrochemiluminescence-based ELISA for the measurement of the oxidative stress biomarker, 3-nitrotyrosine, in human blood serum and cells
Fulltext Access 40 Pages 2018
Deletion of epithelial cell-specific Cdc42 leads to enamel hypermaturation in a conditional knockout mouse model
Fulltext Access 40 Pages 2018
Sodium butyrate attenuates diabetes-induced aortic endothelial dysfunction via P300-mediated transcriptional activation of Nrf2
Fulltext Access 40 Pages 2018
Anxiety-like behavior as an early endophenotype in the TgF344-AD rat model of Alzheimer's disease
Fulltext Access 40 Pages 2018
High- and low-affinity PEGylated hemoglobin-based oxygen carriers: Differential oxidative stress in a Guinea pig transfusion model
Fulltext Access 40 Pages 2018
Mitochondrial pore opening and loss of Ca2 + exchanger NCLX levels occur after frataxin depletion
Fulltext Access 41 Pages 2018
Targeting redox vulnerability of cancer cells by prooxidative intervention of a glutathione-activated Cu(II) pro-ionophore: Hitting three birds with one stone
Fulltext Access 41 Pages 2018
The hippocampal longitudinal axis-relevance for underlying tau and TDP-43 pathology
Fulltext Access 41 Pages 2018
The role of myeloid-derived suppressor cells (MDSC) in the inflammaging process
Fulltext Access 41 Pages 2018
Quercetin preserves redox status and stimulates mitochondrial function in metabolically-stressed HepG2 cells
Fulltext Access 41 Pages 2018
The lysosome system is severely impaired in a cellular model of neurodegeneration induced by HSV-1 and oxidative stress
Fulltext Access 41 Pages 2018
Stress responsive mitochondrial proteins in Arabidopsis thaliana
Fulltext Access 41 Pages 2018
Chemokine CC-motif ligand 2 participates in platelet function and arterial thrombosis by regulating PKCα-P38MAPK-HSP27 pathway
Fulltext Access 41 Pages 2018
Escitalopram alleviates stress-induced Alzheimer's disease-like tau pathologies and cognitive deficits by reducing hypothalamic-pituitary-adrenal axis reactivity and insulin/GSK-3β signal pathway activity
Fulltext Access 41 Pages 2018
A new model of diabetic nephropathy in C57BL/6 mice challenged with advanced oxidation protein products
Fulltext Access 41 Pages 2018
EEG correlates of visual short-term memory in older age vary with adult lifespan cognitive development
Fulltext Access 41 Pages 2018
Attentional ERPs distinguish aging and early Alzheimer's dementia
Fulltext Access 42 Pages 2018
Disturbances in the control of capillary flow in an aged APPswe/PS1ΔE9 model of Alzheimer's disease
Fulltext Access 42 Pages 2018
Intercellular transfer of pathogenic α-synuclein by extracellular vesicles is induced by the lipid peroxidation product 4-hydroxynonenal
Fulltext Access 42 Pages 2018
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