Amyloid-β oligomers synaptotoxicity: The emerging role of EphA4/c-Abl signaling in Alzheimer's disease Fulltext Access 42 Pages 2018
Pro-metastatic activity of AGR2 interrupts angiogenesis target bevacizumab efficiency via direct interaction with VEGFA and activation of NF-κB pathway Fulltext Access 42 Pages 2018
STX3 represses the stability of the tumor suppressor PTEN to activate the PI3K-Akt-mTOR signaling and promotes the growth of breast cancer cells Fulltext Access 42 Pages 2018
The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading Fulltext Access 42 Pages 2018
TAX1BP1 overexpression attenuates cardiac dysfunction and remodeling in STZ-induced diabetic cardiomyopathy in mice by regulating autophagy Fulltext Access 42 Pages 2018
Methylglyoxal displays colorectal cancer-promoting properties in the murine models of azoxymethane and CT26 isografts Fulltext Access 42 Pages 2018
NADPH oxidase 4 and endothelial nitric oxide synthase contribute to endothelial dysfunction mediated by histone methylations in metabolic memory Fulltext Access 42 Pages 2018
Browning of white adipose tissue induced by the Ã3 agonist CL-316,243 after local and systemic treatment - PK-PD relationship Fulltext Access 42 Pages 2018
Mkp-1 protects mice against toxin-induced liver damage by promoting the Nrf2 cytoprotective response Fulltext Access 42 Pages 2018
Resting-state EEG power and connectivity are associated with alpha peak frequency slowing in healthy aging Fulltext Access 42 Pages 2018
Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus Fulltext Access 42 Pages 2018
N-acetylcysteine supplementation increases exercise performance and reduces oxidative stress only in individuals with low levels of glutathione Fulltext Access 42 Pages 2018
Induction of cytochrome P450 4A14 contributes to angiotensin II-induced renal fibrosis in mice Fulltext Access 42 Pages 2018
TGF-β-mediated upregulation of Sox9 in fibroblast promotes renal fibrosis Fulltext Access 43 Pages 2018
Up-regulation of INSR/IGF1R by C-myc promotes TSCC tumorigenesis and metastasis through the NF-κB pathway Fulltext Access 43 Pages 2018
The A to Z of modulated cell patterning by mammalian thioredoxin reductases Fulltext Access 43 Pages 2018
Oxidative cross-linking of proteins to DNA following ischemia-reperfusion injury Fulltext Access 43 Pages 2018
A role of SIPL1/SHARPIN in promoting resistance to hormone therapy in breast cancer Fulltext Access 43 Pages 2018
Oxidative stress reduces trophoblast FOXO1 and integrin β3 expression that inhibits cell motility Fulltext Access 43 Pages 2018
Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging Fulltext Access 43 Pages 2018
Nonsteroidal anti-inflammatory drug, indomethacin improves spatial memory and NMDA receptor function in aged animals Fulltext Access 43 Pages 2018
C-terminal truncation exacerbates the aggregation and cytotoxicity of α-Synuclein: A vicious cycle in Parkinson's disease Fulltext Access 43 Pages 2018
GABA levels and measures of intracortical and interhemispheric excitability in healthy young and older adults: an MRS-TMS study Fulltext Access 43 Pages 2018
Sox9 is increased in arterial plaque and stenosis, associated with synthetic phenotype of vascular smooth muscle cells and causes alterations in extracellular matrix and calcification Fulltext Access 43 Pages 2018
Altered structure and function of fibrinogen after cleavage by Factor VII Activating Protease (FSAP) Fulltext Access 43 Pages 2018
Heterodimer formation by Oct4 and Smad3 differentially regulates epithelial-to-mesenchymal transition-associated factors in breast cancer progression Fulltext Access 43 Pages 2018
Differential effects of short chain fatty acids on endothelial Nlrp3 inflammasome activation and neointima formation: Antioxidant action of butyrate Fulltext Access 43 Pages 2018
Integrative metabolomics and transcriptomics signatures of clinical tolerance to Plasmodium vivax reveal activation of innate cell immunity and T cell signaling Fulltext Access 43 Pages 2018
Pharmacological blockade of CXCR3 by (±)-NBI-74330 reduces neuropathic pain and enhances opioid effectiveness - Evidence from in vivo and in vitro studies Fulltext Access 44 Pages 2018
Increased cortical beta power and spike-wave discharges in middle-aged APP/PS1 mice Fulltext Access 44 Pages 2018
Redox tuning of Ca2+ signaling in microglia drives glutamate release during hypoxia Fulltext Access 44 Pages 2018
Mechanistic study of nonivamide enhancement of hyperthermia-induced apoptosis in U937 cells Fulltext Access 44 Pages 2018
Designing salicylaldehyde isonicotinoyl hydrazones as Cu(II) ionophores with tunable chelation and release of copper for hitting redox Achilles heel of cancer cells Fulltext Access 44 Pages 2018
The cysteine-rich whey protein supplement, Immunocal®, preserves brain glutathione and improves cognitive, motor, and histopathological indices of traumatic brain injury in a mouse model of controlled cortical impact Fulltext Access 44 Pages 2018
Lonicera japonica extends lifespan and healthspan in Caenorhabditis elegans Fulltext Access 44 Pages 2018
Mechanisms of DNA damage repair in adult stem cells and implications for cancer formation Fulltext Access 44 Pages 2018
AMPKα2 deficiency exacerbates long-term PM2.5 exposure-induced lung injury and cardiac dysfunction Fulltext Access 44 Pages 2018
Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome Fulltext Access 44 Pages 2018
Chemical and genetic rescue of an ep300 knockdown model for Rubinstein Taybi Syndrome in zebrafish Fulltext Access 44 Pages 2018
Sustained anti-inflammatory effects of TGF-β1 on microglia/macrophages Fulltext Access 44 Pages 2018
Long non-coding RNA-ATB promotes EMT during silica-induced pulmonary fibrosis by competitively binding miR-200c Fulltext Access 44 Pages 2018
Disruption of endothelial barrier function is linked with hyposecretion and lymphocytic infiltration in salivary glands of Sjögren's syndrome Fulltext Access 45 Pages 2018
Neopterin preconditioning prevents inflammasome activation in mammalian astrocytes Fulltext Access 45 Pages 2018
Heat shock protein A12A encodes a novel prosurvival pathway during ischaemic stroke Fulltext Access 45 Pages 2018
Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis Fulltext Access 45 Pages 2018
Uric acid disrupts hypochlorous acid production and the bactericidal activity of HL-60 cells Fulltext Access 45 Pages 2018
Biliverdin reductase-A impairment links brain insulin resistance with increased Aβ production in an animal model of aging: Implications for Alzheimer disease Fulltext Access 45 Pages 2018
NQO1 regulates mitotic progression and response to mitotic stress through modulating SIRT2 activity Fulltext Access 45 Pages 2018
In vivo mapping of brainstem nuclei functional connectivity disruption in Alzheimer's disease Fulltext Access 45 Pages 2018
The mechanisms underlying olfactory deficits in apolipoprotein E-deficient mice: focus on olfactory epithelium and olfactory bulb Fulltext Access 45 Pages 2018
The GDF11-FTO-PPARγ axis controls the shift of osteoporotic MSC fate to adipocyte and inhibits bone formation during osteoporosis Fulltext Access 45 Pages 2018
Sleep and circadian abnormalities precede cognitive deficits in R521C FUS knockin rats Fulltext Access 45 Pages 2018
Cathelicidin-WA attenuates LPS-induced inflammation and redox imbalance through activation of AMPK signaling Fulltext Access 45 Pages 2018
Mechanical stretch induces antioxidant responses and osteogenic differentiation in human mesenchymal stem cells through activation of the AMPK-SIRT1 signaling pathway Fulltext Access 45 Pages 2018
Aβ truncated species: Implications for brain clearance mechanisms and amyloid plaque deposition Fulltext Access 45 Pages 2018
Dermal fibroblast-to-myofibroblast transition sustained by αvÃ3 integrin-ILK-Snail1/Slug signaling is a common feature for hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders Fulltext Access 45 Pages 2018
S-nitrosoglutathione reductase (GSNOR) inhibitor as an immune modulator in experimental autoimmune encephalomyelitis Fulltext Access 45 Pages 2018
Targeting secreted cytokine BMP9 gates the attenuation of hepatic fibrosis Fulltext Access 45 Pages 2018
Frequency and amplitude modulation of resting-state fMRI signals and their functional relevance in normal aging Fulltext Access 45 Pages 2018
Post-transplant cholangiopathy: Classification, pathogenesis, and preventive strategies Fulltext Access 46 Pages 2018
AMPK/PGC1α activation by melatonin attenuates acute doxorubicin cardiotoxicity via alleviating mitochondrial oxidative damage and apoptosis Fulltext Access 46 Pages 2018
Zac1/GPR39 phosphorylating CaMK-II contributes to the distinct roles of Pax3 and Pax7 in myogenic progression Fulltext Access 46 Pages 2018
Cerebroprotection by salvianolic acid B after experimental subarachnoid hemorrhage occurs via Nrf2- and SIRT1-dependent pathways Fulltext Access 46 Pages 2018
Nogo-B (Reticulon-4B) functions as a negative regulator of the apoptotic pathway through the interaction with c-FLIP in colorectal cancer cells Fulltext Access 46 Pages 2018
Early minor stimulation of microglial TLR2 and TLR4 receptors attenuates Alzheimer's disease-related cognitive deficit in rats: behavioral, molecular, and electrophysiological evidence Fulltext Access 46 Pages 2018
Up-regulation of NOX1/NADPH oxidase following drug-induced myocardial injury promotes cardiac dysfunction and fibrosis Fulltext Access 46 Pages 2018
The G protein-coupled P2Y6 receptor promotes colorectal cancer tumorigenesis by inhibiting apoptosis Fulltext Access 46 Pages 2018
SIRT6 protects against hepatic ischemia/reperfusion injury by inhibiting apoptosis and autophagy related cell death Fulltext Access 46 Pages 2018
Atomic structure and enzymatic insights into the vancomycin-resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit C Fulltext Access 46 Pages 2018
A copper-deficient form of mutant Cu/Zn-superoxide dismutase as an early pathological species in amyotrophic lateral sclerosis Fulltext Access 47 Pages 2018
APP/Go protein Gβγ-complex signaling mediates Aβ degeneration and cognitive impairment in Alzheimer's disease models Fulltext Access 47 Pages 2018
Strategies to decrease oxidative stress biomarker levels in human medical conditions: A meta-analysis on 8-iso-prostaglandin F2α Fulltext Access 47 Pages 2018
Phloroglucinol ameliorates cognitive impairments by reducing the amyloid β peptide burden and pro-inflammatory cytokines in the hippocampus of 5XFAD mice Fulltext Access 47 Pages 2018
Autoimmunity in multiple sclerosis: role of sphingolipids, invariant NKT cells and other immune elements in control of inflammation and neurodegeneration Fulltext Access 47 Pages 2018
Protecting the heart through MK2 modulation, toward a role in diabetic cardiomyopathy and lipid metabolism Fulltext Access 48 Pages 2018
Age dependent variations in the deep brain photoreceptors (DBPs), GnRH-GnIH system and testicular steroidogenesis in Japanese quail, Coturnix coturnix japonica Fulltext Access 48 Pages 2018
Inducible overexpression of endothelial proNGF as a mouse model to study microvascular dysfunction Fulltext Access 48 Pages 2018
ERK1/2/mTOR/Stat3 pathway-mediated autophagy alleviates traumatic brain injury-induced acute lung injury Fulltext Access 48 Pages 2018
PGC-1α sparks the fire of neuroprotection against neurodegenerative disorders Fulltext Access 48 Pages 2018
Alterations of functional circuitry in aging brain and the impact of mutated APP expression Fulltext Access 49 Pages 2018
Altered glutamate clearance in ascorbate deficient mice increases seizure susceptibility and contributes to cognitive impairment in APP/PSEN1 mice Fulltext Access 49 Pages 2018
Multifaceted remodeling by vitamin C boosts sensitivity of Mycobacterium tuberculosis subpopulations to combination treatment by anti-tubercular drugs Fulltext Access 49 Pages 2018
Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage Fulltext Access 49 Pages 2018
Mitochondrial ATP-sensitive potassium channel regulates mitochondrial dynamics to participate in neurodegeneration of Parkinson's disease Fulltext Access 49 Pages 2018
O-GlcNAcylation and neuronal energy status: Implications for Alzheimer's disease Fulltext Access 50 Pages 2018
Axin-2 knockdown promote mitochondrial biogenesis and dopaminergic neurogenesis by regulating Wnt/β-catenin signaling in rat model of Parkinson's disease Fulltext Access 50 Pages 2018
NASP antagonize chromatin accessibility through maintaining histone H3K9me1 in hepatocellular carcinoma Fulltext Access 50 Pages 2018
Caffeic acid attenuates rat liver injury after transplantation involving PDIA3-dependent regulation of NADPH oxidase Fulltext Access 50 Pages 2018
Mechanisms involved in the death of steatotic WIF-B9 hepatocytes co-exposed to benzo[a]pyrene and ethanol: a possible key role for xenobiotic metabolism and nitric oxide Fulltext Access 50 Pages 2018
Secretome from hypoxia-conditioned adipose-derived mesenchymal stem cells promotes the healing of gastric mucosal injury in a rodent model Fulltext Access 50 Pages 2018
An alternative transcript of the Alzheimer's disease risk gene SORL1 encodes a truncated receptor Fulltext Access 51 Pages 2018