The MELAS mutation m.3243A>G promotes reactivation of fetal cardiac genes and an epithelial-mesenchymal transition-like program via dysregulation of miRNAs Fulltext Access 52 Pages 2018
ROS-dependent signalling pathways in plants and algae exposed to high light: Comparisons with other eukaryotes Fulltext Access 52 Pages 2018
Axed MUC4 (MUC4/X) aggravates pancreatic malignant phenotype by activating integrin-β1/FAK/ERK pathway Fulltext Access 52 Pages 2018
Renal outcomes with sodium glucose cotransporter 2 (SGLT2) inhibitor, dapagliflozin, in obese insulin-resistant model Fulltext Access 52 Pages 2018
The hypothalamus as the primary brain region of metabolic abnormalities in APP/PS1 transgenic mouse model of Alzheimer's disease Fulltext Access 52 Pages 2018
β-Lapachone and its iodine derivatives cause cell cycle arrest at G2/M phase and reactive oxygen species-mediated apoptosis in human oral squamous cell carcinoma cells Fulltext Access 52 Pages 2018
Nrf2/ARE pathway attenuates oxidative and apoptotic response in human osteoarthritis chondrocytes by activating ERK1/2/ELK1-P70S6K-P90RSK signaling axis Fulltext Access 52 Pages 2018
Aggregation of α- and β- caseins induced by peroxyl radicals involves secondary reactions of carbonyl compounds as well as di-tyrosine and di-tryptophan formation Fulltext Access 52 Pages 2018
PINK1 Protects Auditory Hair Cells and Spiral Ganglion Neurons from Cisplatin-induced Ototoxicity via Inducing Autophagy and Inhibiting JNK Signaling Pathway Fulltext Access 53 Pages 2018
Nitric oxide synthase 2 enhances the survival of mice during Salmonella Typhimurium infection-induced sepsis by increasing reactive oxygen species, inflammatory cytokines and recruitment of neutrophils to the peritoneal cavity Fulltext Access 53 Pages 2018
DNA methylation dynamics in aging: how far are we from understanding the mechanisms? Fulltext Access 53 Pages 2018
Trehalose protects against oxidative stress by regulating the Keap1-Nrf2 and autophagy pathways Fulltext Access 53 Pages 2018
STAT3-RXR-Nrf2 activates systemic redox and energy homeostasis upon steep decline in pO2 gradient Fulltext Access 53 Pages 2018
Cx26 partial loss causes accelerated presbycusis by redox imbalance and dysregulation of Nfr2 pathway Fulltext Access 53 Pages 2018
Cln3 function is linked to osmoregulation in a Dictyostelium model of Batten disease Fulltext Access 54 Pages 2018
Protective outcomes of low-dose doxycycline on renal function of Wistar rats subjected to acute ischemia/reperfusion injury Fulltext Access 55 Pages 2018
Endogenous osteopontin induces myocardial CCL5 and MMP-2 activation that contributes to inflammation and cardiac remodeling in a mouse model of chronic Chagas heart disease Fulltext Access 55 Pages 2018
Insulin-like Growth Factor 1 (IGF-1) as a marker of cognitive decline in normal ageing: A review Fulltext Access 56 Pages 2018
PD-L1 confers glioblastoma multiforme malignancy via Ras binding and Ras/Erk/EMT activation Fulltext Access 56 Pages 2018
Interleukin-1β and tumor necrosis factor-α augment acidosis-induced rat articular chondrocyte apoptosis via nuclear factor-kappaB-dependent upregulation of ASIC1a channel Fulltext Access 57 Pages 2018
The influence and impact of ageing and immunosenescence (ISC) on adaptive immunity during multiple sclerosis (MS) and the animal counterpart experimental autoimmune encephalomyelitis (EAE) Fulltext Access 57 Pages 2018
Perinatal α-tocopherol overload programs alterations in kidney development and renal angiotensin II signaling pathways at birth and at juvenile age: Mechanisms underlying the development of elevated blood pressure Fulltext Access 58 Pages 2018
Anthocyanins and their gut metabolites attenuate monocyte adhesion and transendothelial migration through nutrigenomic mechanisms regulating endothelial cell permeability Fulltext Access 59 Pages 2018
Altered function of neuronal L-type calcium channels in ageing and neuroinflammation: Implications in age-related synaptic dysfunction and cognitive decline Fulltext Access 59 Pages 2018
Targeting the 15-keto-PGE2-PTGR2 axis modulates systemic inflammation and survival in experimental sepsis Fulltext Access 59 Pages 2018
Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral sclerosis Fulltext Access 60 Pages 2018
Neuroprotection afforded by circadian regulation of intracellular glutathione levels: A key role for miRNAs Fulltext Access 61 Pages 2018
The 3-phenylcoumarin derivative 6,7-dihydroxy-3-[3â²,4â²-methylenedioxyphenyl]-coumarin downmodulates the FcγR- and CR-mediated oxidative metabolism and elastase release in human neutrophils: Possible mechanisms underlying inhibition of the formation a Fulltext Access 61 Pages 2018
Identification of differential phosphorylation and sub-cellular localization of the metastasis suppressor, NDRG1 Fulltext Access 62 Pages 2018
Werner syndrome (WRN) gene variants and their association with altered function and age-associated diseases Fulltext Access 62 Pages 2018
FOXO1 inhibition potentiates endothelial angiogenic functions in diabetes via suppression of ROCK1/Drp1-mediated mitochondrial fission Fulltext Access 63 Pages 2018
Structural and functional changes in RNAse A originating from tyrosine and histidine cross-linking and oxidation induced by singlet oxygen and peroxyl radicals Fulltext Access 63 Pages 2018
ERK1/2 activated PHLPP1 induces skeletal muscle ER stress through the inhibition of a novel substrate AMPK Fulltext Access 64 Pages 2018
H2O2 metabolism in liver and heart mitochondria: Low emitting-high scavenging and high emitting-low scavenging systems Fulltext Access 65 Pages 2018
Procyanidin B2 ameliorates free fatty acids-induced hepatic steatosis through regulating TFEB-mediated lysosomal pathway and redox state Fulltext Access 65 Pages 2018
Alternative translation initiation of Caveolin-2 desensitizes insulin signaling through dephosphorylation of insulin receptor by PTP1B and causes insulin resistance Fulltext Access 68 Pages 2018
Role of D-galactose-induced brain aging and its potential used for therapeutic interventions Fulltext Access 71 Pages 2018
Abnormalities of resting-state functional cortical connectivity in patients with dementia due to Alzheimer's and Lewy body diseases: an EEG study Fulltext Access 74 Pages 2018
Serum proteome mapping of EGF transgenic mice reveal mechanistic biomarkers of lung cancer precursor lesions with clinical significance for human adenocarcinomas Fulltext Access 76 Pages 2018
Aplicación clÃnica del test «Detenerse al andar mientras se habla» (Stop walking while talking test). Relación con parámetros funcionales y otras pruebas de marcha y equilibrio Fulltext Access 4 Pages 2017
Utilidad del Ãndice FEV1/FEV6 en pacientes pluripatológicos hospitalizados para detectar la prevalencia de obstrucción pulmonar Fulltext Access 4 Pages 2017
Flavan 3-ol delays the progression of disuse atrophy induced by hindlimb suspension in mice Fulltext Access 4 Pages 2017
Ansiedad en las personas mayores de 50 años. Datos de un estudio representativo de la población mayor en España Fulltext Access 4 Pages 2017
Blood DNA methylation age is not associated with cognitive functioning in middle-aged monozygotic twins Fulltext Access 4 Pages 2017
Declive funcional y presencia de sÃntomas en cuidados paliativos: ¿causa o consecuencia? Fulltext Access 4 Pages 2017
Emerging therapeutic modalities for acute myeloid leukemia (AML) in older adults Fulltext Access 4 Pages 2017
NEDA treatment target? No evident disease activity as an actionable outcome in practice Fulltext Access 4 Pages 2017
GCH1 mutations are common in Serbian patients with dystonia-parkinsonism: Challenging previously reported prevalence rates of DOPA-responsive dystonia Fulltext Access 4 Pages 2017
Modelo de prescripción centrado en la persona para mejorar la adecuación y adherencia terapéutica en los pacientes con multimorbilidad Fulltext Access 4 Pages 2017
Factores predictores de pérdida funcional al alta en ancianos hospitalizados por enfermedad aguda Fulltext Access 4 Pages 2017
SNCA mutation p.Ala53Glu is derived from a common founder in the Finnish population Fulltext Access 4 Pages 2017
A novel presenilin 1 mutation (F388L) identified in a Chinese family with early-onset Alzheimer's disease Fulltext Access 4 Pages 2017
Locomotor activity and the expression of orexin A and orexin B in aged female rhesus macaques Fulltext Access 4 Pages 2017
MOG-IgG-positive multifocal myelitis with intrathecal IgG synthesis as a spectrum associated with MOG autoimmunity: Two case reports Fulltext Access 4 Pages 2017
Monitoring CD27Â + memory B-cells in neuromyelitis optica spectrum disorders patients treated with rituximab: Results from a bicentric study Fulltext Access 4 Pages 2017
Corrigendum to “The utility of diffusion MRI with quantitative ADC measurements for differentiating high-grade from low-grade cerebral gliomas: Evidence from a meta-analysis” [J. Neurol. Sci. 373 (2017) 9-15] Fulltext Access 4 Pages 2017
RNF213 rs112735431 polymorphism in intracranial artery steno-occlusive disease and moyamoya disease in Koreans Fulltext Access 4 Pages 2017
TNF-alpha inhibitor associated myelopathies: A neurological complication in patients with rheumatologic disorders Fulltext Access 4 Pages 2017
First reported cases of anti-NMDA receptor encephalitis in Vietnamese adolescents and adults Fulltext Access 4 Pages 2017
Thalamic involvement determined using VSRAD advance on MRI and easy Z-score analysis of 99mTc-ECD-SPECT in Gerstmann-Sträussler-Scheinker syndrome with P102L mutation Fulltext Access 4 Pages 2017
The heterozygous R1441C mutation of leucine-rich repeat kinase 2 gene in a Chinese patient with Parkinson disease: A five-year follow-up and literatures review Fulltext Access 4 Pages 2017
Menopausal hormone therapy may increase non-allergic rhinitis among postmenopausal women: Results from the Korea National Health and Nutrition Examination Survey (2010-2012) Fulltext Access 4 Pages 2017
Autosomal Recessive Cerebellar Ataxia type 1 mimicking multiple sclerosis: A report of two siblings with a novel mutation in SYNE1 gene in a Saudi family Fulltext Access 4 Pages 2017
Quantitative analysis of brain atrophy in patients with xeroderma pigmentosum group A carrying the founder mutation in Japan Fulltext Access 4 Pages 2017
Novel biallelic missense mutations in CTC1 gene identified in a Chinese family with Coats plus syndrome Fulltext Access 4 Pages 2017
About 30% of wake-up stroke patients may be candidate for the tPA therapy using Negative-FLAIR as a “tissue clock” Fulltext Access 4 Pages 2017
A case report of multiple system atrophy treated with an Abelson tyrosine kinase inhibitor Fulltext Access 4 Pages 2017
Comment on “Serum uric acid is associated with better executive function in men but not in women: Baseline assessment of the ELSA-Brasil study” Fulltext Access 4 Pages 2017
Preface to the Special Issue on 4-Hydroxynonenal and Related Lipid Oxidation Products Fulltext Access 4 Pages 2017
Editorial Introduction to the Special Issue on 4-Hydroxynonenal and Related Lipid Oxidation Products Fulltext Access 4 Pages 2017
Review ArticleAssay of superoxide dismutase activity in a plate assay using WST-1 Fulltext Access 4 Pages 2017
Further psychometric validation of the GAH scale: Responsiveness and effect size Fulltext Access 4 Pages 2017
Negative myoclonus induced by gabapentin and pregabalin: A case series and systematic literature review Fulltext Access 4 Pages 2017
Absence of regulator of G-protein signaling 4 does not protect against dopamine neuron dysfunction and injury in the mouse 6-hydroxydopamine lesion model of Parkinson's disease Fulltext Access 4 Pages 2017
PatologÃa asociada al deterioro cognitivo leve. Factores de riesgo y predictivos Fulltext Access 4 Pages 2017
A sensitive and practical RP-HPLC-FLD for determination of the low neuroactive amino acid levels in body fluids and its application in depression Fulltext Access 4 Pages 2017
Laughter is the best medicine: The Second City® improvisation as an intervention for Parkinson's disease Fulltext Access 4 Pages 2017
SCA2 family presenting as typical Parkinson's disease: 34 year follow up Fulltext Access 4 Pages 2017
Orthostatic myoclonus after brain tumor radiation: Insights from two lesional cases Fulltext Access 4 Pages 2017
A multifaceted role for MOF histone modifying factor in genome maintenance Fulltext Access 4 Pages 2017
Centenarians as a 21st century healthy aging model: A legacy of humanity and the need for a world-wide consortium (WWC100+) Fulltext Access 4 Pages 2017