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Daneshyari Ageing Journas Latest Articles

Ageing Research Articles

Original articleAspirin plus sorafenib potentiates cisplatin cytotoxicity in resistant head and neck cancer cells through xCT inhibition
Fulltext Access 9 Pages 2017
Cancer growth regulation by 4-hydroxynonenal
Fulltext Access 9 Pages 2017
Role of 4-hydroxy-2-nonenal (HNE) in the pathogenesis of alzheimer disease and other selected age-related neurodegenerative disorders
Fulltext Access 9 Pages 2017
Mesna (2-mercaptoethane sodium sulfonate) functions as a regulator of myeloperoxidase
Fulltext Access 9 Pages 2017
TRPV4 calcium-permeable channel is a novel regulator of oxidized LDL-induced macrophage foam cell formation
Fulltext Access 9 Pages 2017
Endogenous hydrogen sulfide-mediated MAPK inhibition preserves endothelial function through TXNIP signaling
Fulltext Access 9 Pages 2017
Examining a role for PKG Iα oxidation in the pathogenesis of cardiovascular dysfunction during diet-induced obesity
Fulltext Access 9 Pages 2017
Rheostatic CD44 isoform expression and its association with oxidative stress in human malignant mesothelioma
Fulltext Access 9 Pages 2017
Contribution of guanine nucleotide exchange factor Vav2 to NLRP3 inflammasome activation in mouse podocytes during hyperhomocysteinemia
Fulltext Access 9 Pages 2017
Regulation of STAT3 and NF-κB activations by S-nitrosylation in multiple myeloma
Fulltext Access 9 Pages 2017
Removal of oxidatively generated DNA damage by overlapping repair pathways
Fulltext Access 9 Pages 2017
Oxidatively-generated damage to DNA and proteins mediated by photosensitized UVA
Fulltext Access 9 Pages 2017
Hide and seek: How do DNA glycosylases locate oxidatively damaged DNA bases amidst a sea of undamaged bases?
Fulltext Access 9 Pages 2017
Review ArticleRole of the oxidized form of XRCC1 in protection against extreme oxidative stress
Fulltext Access 9 Pages 2017
Mitogen-activated protein kinase phosphatase 1 (MKP-1) in macrophage biology and cardiovascular disease. A redox-regulated master controller of monocyte function and macrophage phenotype
Fulltext Access 9 Pages 2017
Redox regulation of electrophilic signaling by reactive persulfides in cardiac cells
Fulltext Access 9 Pages 2017
Convergent and divergent effects of apolipoprotein E ε4 and ε2 alleles on amygdala functional networks in nondemented older adults
Fulltext Access 9 Pages 2017
Oxidized and Original article degraded mitochondrial polynucleotides (DeMPs), especially RNA, are potent immunogenic regulators in primary mouse macrophages
Fulltext Access 9 Pages 2017
Sirt3 confers protection against neuronal ischemia by inducing autophagy: Involvement of the AMPK-mTOR pathway
Fulltext Access 9 Pages 2017
Click-PEGylation - A mobility shift approach to assess the redox state of cysteines in candidate proteins
Fulltext Access 9 Pages 2017
Nitric oxide-regulated proteolysis of human CYP2B6 via the ubiquitin-proteasome system
Fulltext Access 9 Pages 2017
Docetaxel plus gemcitabine versus gemcitabine in elderly patients with advanced non-small cell lung cancer and use of a geriatric assessment: Lessons from a prematurely closed Hellenic Oncology Research Group randomized phase III study
Fulltext Access 9 Pages 2017
Spinal nerve involvement in early Guillain-Barré syndrome: The Haymaker and Kernohan's legacy
Fulltext Access 9 Pages 2017
Cerebral hyperperfusion syndrome and intracranial hemorrhage after carotid endarterectomy or carotid stenting: A meta-analysis
Fulltext Access 9 Pages 2017
Video-EEG findings in acute bithalamic-midbrain ischemia
Fulltext Access 9 Pages 2017
ROS-AKT-mTOR axis mediates autophagy of human umbilical vein endothelial cells induced by cooking oil fumes-derived fine particulate matters in vitro
Fulltext Access 9 Pages 2017
Mitochondrial catalase induces cells transformation through nucleolin-dependent Cox-2 mRNA stabilization
Fulltext Access 9 Pages 2017
Mitochondrial targeted curcumin exhibits anticancer effects through disruption of mitochondrial redox and modulation of TrxR2 activity
Fulltext Access 9 Pages 2017
SOD2 gene polymorphism may modulate biochemical responses to a 12-week swimming training
Fulltext Access 9 Pages 2017
Cannabidiol attenuates OGD/R-induced damage by enhancing mitochondrial bioenergetics and modulating glucose metabolism via pentose-phosphate pathway in hippocampal neurons
Fulltext Access 9 Pages 2017
Constitutive activation of Nrf2 induces a stable reductive state in the mouse myocardium
Fulltext Access 9 Pages 2017
In vivo prion models and the disconnection between transmissibility and neurotoxicity
Fulltext Access 9 Pages 2017
Excessive tau accumulation in the parieto-occipital cortex characterizes early-onset Alzheimer's disease
Fulltext Access 9 Pages 2017
APOE ε4 status is associated with white matter hyperintensities volume accumulation rate independent of AD diagnosis
Fulltext Access 9 Pages 2017
Lack of evidence for a role of genetic variation in TMEM230 in the risk for Parkinson's disease in the Caucasian population
Fulltext Access 9 Pages 2017
Presenilin 1 mutations influence processing and trafficking of the ApoE receptor apoER2
Fulltext Access 9 Pages 2017
Lack of association of mortalin (HSPA9) and other mitochondria-related genes with risk of Parkinson's and Alzheimer's diseases
Fulltext Access 9 Pages 2017
Evaluation of the interaction between LRRK2 and PARK16 loci in determining risk of Parkinson's disease: analysis of a large multicenter study
Fulltext Access 9 Pages 2017
The dementia-associated APOE ε4 allele is not associated with rapid eye movement sleep behavior disorder
Fulltext Access 9 Pages 2017
A cluster of progranulin C157KfsX97 mutations in Southern Italy: clinical characterization and genetic correlations
Fulltext Access 9 Pages 2017
Índice frágil-VIG: diseño y evaluación de un índice de fragilidad basado en la Valoración Integral Geriátrica
Fulltext Access 9 Pages 2017
Efectividad de las intervenciones dirigidas a reducir las sujeciones físicas en personas mayores de 65 años institucionalizadas: una revisión sistemática
Fulltext Access 9 Pages 2017
¿Mides la velocidad de la marcha en tu práctica diaria? Una revisión
Fulltext Access 9 Pages 2017
Estudio Octabaix. Sumario de la valoración inicial y 5 años de seguimiento
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Sirtuins, epigenetics and longevity
Fulltext Access 9 Pages 2017
ALBA Screening Instrument (ASI): A brief screening tool for Lewy Body Dementia
Fulltext Access 9 Pages 2017
Cognitive decline and brain amyloid-β accumulation across 3 years in adults with Down syndrome
Fulltext Access 9 Pages 2017
Age-related alterations in hypothalamic kisspeptin, neurokinin B, and dynorphin neurons and in pulsatile LH release in female and male rats
Fulltext Access 9 Pages 2017
Regular articleOligomeric amyloid-β peptide disrupts olfactory information output by impairment of local inhibitory circuits in rat olfactory bulb
Fulltext Access 9 Pages 2017
Regular articleIncreased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype
Fulltext Access 9 Pages 2017
The biomarker-based diagnosis of Alzheimer's disease. 1—ethical and societal issues
Fulltext Access 9 Pages 2017
Executive function performance and change in aging is predicted by apolipoprotein E, intensified by catechol-O-methyltransferase and brain-derived neurotrophic factor, and moderated by age and lifestyle
Fulltext Access 9 Pages 2017
Effect of short-term DHEA supplementation on serum and hippocampal estrogen concentrations in perimenopausal female rhesus macaques
Fulltext Access 9 Pages 2017
ATXN2 trinucleotide repeat length correlates with risk of ALS
Fulltext Access 9 Pages 2017
The Down syndrome brain in the presence and absence of fibrillar β-amyloidosis
Fulltext Access 9 Pages 2017
TMEM230 in Parkinson's disease
Fulltext Access 9 Pages 2017
Leucine-rich α2-glycoprotein overexpression in the brain contributes to memory impairment
Fulltext Access 9 Pages 2017
The HRH4 rs11662595 mutation is associated with histamine H4 receptor dysfunction and with increased epithelial-to-mesenchymal transition progress in non-small cell lung cancer
Fulltext Access 10 Pages 2017
The antiepileptogenic effect of low-frequency stimulation on perforant path kindling involves changes in regulators of G-protein signaling in rat
Fulltext Access 10 Pages 2017
Inhibition of insulin/PI3K/AKT signaling decreases adipose Sortilin 1 in mice and 3 T3-L1 adipocytes
Fulltext Access 10 Pages 2017
HDAC inhibitors: A new promising drug class in anti-aging research
Fulltext Access 10 Pages 2017
CTT1 overexpression increases the replicative lifespan of MMS-sensitive Saccharomyces cerevisiae deficient in KSP1
Fulltext Access 10 Pages 2017
Original articleA brewing understanding of the regulation of Bax function by Bcl-xL and Bcl-2
Fulltext Access 10 Pages 2017
The effect of hormone replacement therapy and tibolone on lipoprotein (a) concentrations in postmenopausal women: A systematic review and meta-analysis
Fulltext Access 10 Pages 2017
Quercetin suppresses NLRP3 inflammasome activation in epithelial cells triggered by Escherichia coli O157:H7
Fulltext Access 10 Pages 2017
Ergothioneine stands out from hercynine in the reaction with singlet oxygen: Resistance to glutathione and TRIS in the generation of specific products indicates high reactivity
Fulltext Access 10 Pages 2017
Impaired cross-talk between the thioredoxin and glutathione systems is related to ASK-1 mediated apoptosis in neuronal cells exposed to mercury
Fulltext Access 10 Pages 2017
Cysteine residues 244 and 458-459 within the catalytic subunit of Na,K-ATPase control the enzyme's hydrolytic and signaling function under hypoxic conditions
Fulltext Access 10 Pages 2017
Ripk3 induces mitochondrial apoptosis via inhibition of FUNDC1 mitophagy in cardiac IR injury
Fulltext Access 10 Pages 2017
Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase
Fulltext Access 10 Pages 2017
Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice
Fulltext Access 10 Pages 2017
Butyrate induces ROS-mediated apoptosis by modulating miR-22/SIRT-1 pathway in hepatic cancer cells
Fulltext Access 10 Pages 2017
Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells
Fulltext Access 10 Pages 2017
Cysteine persulfides and polysulfides produced by exchange reactions with H2S protect SH-SY5Y cells from methylglyoxal-induced toxicity through Nrf2 activation
Fulltext Access 10 Pages 2017
Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells
Fulltext Access 10 Pages 2017
Non-electron transfer chain mitochondrial defects differently regulate HIF-1α degradation and transcription
Fulltext Access 10 Pages 2017
Vitamin D in liver disease: Current evidence and potential directions
Fulltext Access 10 Pages 2017
HNE and cholesterol oxidation products in colorectal inflammation and carcinogenesis
Fulltext Access 10 Pages 2017
Pro-apoptotic effects of lipid oxidation products: HNE at the crossroads of NF-κB pathway and anti-apoptotic Bcl-2
Fulltext Access 10 Pages 2017
Targeting GPCR-Gβγ-GRK2 signaling as a novel strategy for treating cardiorenal pathologies
Fulltext Access 10 Pages 2017
Therapeutic relevance of mTOR inhibition in murine succinate semialdehyde dehydrogenase deficiency (SSADHD), a disorder of GABA metabolism
Fulltext Access 10 Pages 2017
Enzymatic and free radical formation of cis- and trans- epoxyeicosatrienoic acids in vitro and in vivo
Fulltext Access 10 Pages 2017
Bcl-xL knockout attenuates mitochondrial respiration and causes oxidative stress that is compensated by pentose phosphate pathway activity
Fulltext Access 10 Pages 2017
Hydrogen sulfide-producing cystathionine γ-lyase is critical in the progression of kidney fibrosis
Fulltext Access 10 Pages 2017
Potential role of ferric hemoglobin in MS pathogenesis: Effects of oxidative stress and extracellular methemoglobin or its degradation products on myelin components
Fulltext Access 10 Pages 2017
Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals
Fulltext Access 10 Pages 2017
5-Lipoxygenase in monocytes emerges as a therapeutic target for intimal hyperplasia in a murine wire-injured femoral artery
Fulltext Access 10 Pages 2017
Identification of a flavonoid C-glycoside as potent antioxidant
Fulltext Access 10 Pages 2017
Tempol (4 hydroxy-tempo) inhibits anoxia-induced progression of mitochondrial dysfunction and associated neurobehavioral impairment in neonatal rats
Fulltext Access 10 Pages 2017
SRB1 as a new redox target of cigarette smoke in human sebocytes
Fulltext Access 10 Pages 2017
Cytochrome P450 enzymes but not NADPH oxidases are the source of the NADPH-dependent lucigenin chemiluminescence in membrane assays
Fulltext Access 10 Pages 2017
Monocyte activation drives preservation of membrane thiols by promoting release of oxidised membrane moieties via extracellular vesicles
Fulltext Access 10 Pages 2017
The NRF2 activator DH404 attenuates adverse ventricular remodeling post-myocardial infarction by modifying redox signalling
Fulltext Access 10 Pages 2017
Oxidized 5-aminosalicylic acid activates Nrf2-HO-1 pathway by covalently binding to Keap1: Implication in anti-inflammatory actions of 5-aminosalicylic acid
Fulltext Access 10 Pages 2017
The association of heart failure-related microRNAs with neurohormonal signaling
Fulltext Access 10 Pages 2017
Yap1p, the central regulator of the S. cerevisiae oxidative stress response, is activated by allicin, a natural oxidant and defence substance of garlic
Fulltext Access 10 Pages 2017
Review ArticleEpigenetic regulation of redox signaling in diabetic retinopathy: Role of Nrf2
Fulltext Access 10 Pages 2017
Sigma-1 receptor in brain ischemia/reperfusion: Possible role in the NR2A-induced pathway to regulate brain-derived neurotrophic factor
Fulltext Access 10 Pages 2017
Localization of a mutant SOD1 protein in E40K-heterozygous dogs: Implications for non-cell-autonomous pathogenesis of degenerative myelopathy
Fulltext Access 10 Pages 2017
Acquired pendular nystagmus
Fulltext Access 10 Pages 2017
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