Gut microbiota: A player in aging and a target for anti-aging intervention Fulltext Access 10 Pages 2017
Aberrant spontaneous low-frequency brain activity in amnestic mild cognitive impairment: A meta-analysis of resting-state fMRI studies Fulltext Access 10 Pages 2017
Cáncer colorrectal en el anciano. Tratamiento quirúrgico, quimioterápico y aportación desde la geriatrÃa Fulltext Access 10 Pages 2017
Aging reduces the high-frequency and short-term adaptation of the vestibulo-ocular reflex in mice Fulltext Access 10 Pages 2017
Tremor's glove-an innovative electrical muscle stimulation therapy for intractable tremor in Parkinson's disease: A randomized sham-controlled trial Fulltext Access 10 Pages 2017
The anteroposterior and primary-to-posterior limbic ratios as MRI-derived volumetric markers of Alzheimer's disease Fulltext Access 10 Pages 2017
Regular articleSirtuin 2 enhances dopaminergic differentiation via the AKT/GSK-3β/β-catenin pathway Fulltext Access 10 Pages 2017
Novel UBQLN2 mutations linked to amyotrophic lateral sclerosis and atypical hereditary spastic paraplegia phenotype through defective HSP70-mediated proteolysis Fulltext Access 10 Pages 2017
EEG spectral analysis as a putative early prognostic biomarker in nondemented, amyloid positive subjects Fulltext Access 10 Pages 2017
ApoE influences regional white-matter axonal density loss in Alzheimer's disease Fulltext Access 10 Pages 2017
Chemotherapy-induced (febrile) neutropenia prophylaxis with biosimilar filgrastim in elderly versus non-elderly cancer patients: Patterns, outcomes, and determinants (MONITOR-GCSF study) Fulltext Access 10 Pages 2017
Association between CSF biomarkers, hippocampal volume and cognitive function in patients with amnestic mild cognitive impairment (MCI) Fulltext Access 10 Pages 2017
In old BALB/c mice, bone marrow pre-B cell and surrogate light chain reduction is associated with increased B cell reactivity to phosphorylcholine, but reduced T15 idiotype dominance Fulltext Access 10 Pages 2017
Molecular pathophysiology of impaired glucose metabolism, mitochondrial dysfunction, and oxidative DNA damage in Alzheimer's disease brain Fulltext Access 10 Pages 2017
White light emitting diode suppresses proliferation and induces apoptosis in hippocampal neuron cells through mitochondrial cytochrome c oxydase-mediated IGF-1 and TNF-α pathways Fulltext Access 11 Pages 2017
Smart watch, smarter EDSS: Improving disability assessment in multiple sclerosis clinical practice Fulltext Access 11 Pages 2017
Nitration-mediated deficiency of cystathionine β-synthase activity accelerates the progression of hyperhomocysteinemia Fulltext Access 11 Pages 2017
A chronic increase of corticosterone age-dependently reduces systemic DNA damage from oxidation in rats Fulltext Access 11 Pages 2017
Respiratory syncytial virus induces NRF2 degradation through a promyelocytic leukemia protein â ring finger protein 4 dependent pathway Fulltext Access 11 Pages 2017
Linking Alzheimer's disease and type 2 diabetes: Novel shared susceptibility genes detected by cFDR approach Fulltext Access 11 Pages 2017
Siderophore-mediated iron acquisition and modulation of host-bacterial interactions Fulltext Access 11 Pages 2017
How widespread is stable protein S-nitrosylation as an end-effector of protein regulation? Fulltext Access 11 Pages 2017
Organizers and activators: Cytosolic Nox proteins impacting on vascular function Fulltext Access 11 Pages 2017
Causes of failure of pallidal deep brain stimulation in cases with pre-operative diagnosis of isolated dystonia Fulltext Access 11 Pages 2017
Chromatin associated mechanisms in base excision repair - nucleosome remodeling and DNA transcription, two key players Fulltext Access 11 Pages 2017
The cyclopurine deoxynucleosides: DNA repair, biological effects, mechanistic insights, and unanswered questions Fulltext Access 11 Pages 2017
Ultraviolet A-induced oxidation in cornea: Characterization of the early oxidation-related events Fulltext Access 11 Pages 2017
Dysfunction of mitochondrial Lon protease and identification of oxidized protein in mouse brain following exposure to MPTP: Implications for Parkinson disease Fulltext Access 11 Pages 2017
Akt1/NFκB signaling pathway activation by a small molecule DMA confers radioprotection to intestinal epithelium in xenograft model Fulltext Access 11 Pages 2017
IgLON5 autoimmunity tested negative in patients with progressive supranuclear palsy and corticobasal syndrome Fulltext Access 11 Pages 2017
Advancing stroke genomic research in the age of Trans-Omics big data science: Emerging priorities and opportunities Fulltext Access 11 Pages 2017
SMART syndrome with cerebral angiographic abnormalities - A case report Fulltext Access 11 Pages 2017
Carbon monoxide protects against hepatic steatosis in mice by inducing sestrin-2 via the PERK-eIF2α-ATF4 pathway Fulltext Access 11 Pages 2017
MtDNA m.3472TÂ >Â C could be classified as a primary mutation of Leber's hereditary optic neuropathy Fulltext Access 11 Pages 2017
Three novel missense mutations in SLC20A2 associated with idiopathic basal ganglia calcification Fulltext Access 11 Pages 2017
Cervical spinal cord and motor unit pathology in a canine model of SOD1-associated amyotrophic lateral sclerosis Fulltext Access 11 Pages 2017
Association between human herpesvirus & human endogenous retrovirus and MS onset & progression Fulltext Access 11 Pages 2017
Marked hypertriglyceridemia induced by interferon-β1a therapy in a clinically isolated syndrome patient Fulltext Access 11 Pages 2017
Nicotinamide supplementation phenocopies SIR2 inactivation by modulating carbon metabolism and respiration during yeast chronological aging Fulltext Access 11 Pages 2017
Wall-eyed bilateral internuclear ophtalmoplegia (WEBINO) in a patient with Richardson's syndrome - Progressive supranuclear palsy Fulltext Access 11 Pages 2017
RNA sequencing reveals pronounced changes in the noncoding transcriptome of aging synaptosomes Fulltext Access 11 Pages 2017
Lipid-induced endoplasmic reticulum stress in X-linked adrenoleukodystrophy Fulltext Access 11 Pages 2017
UCP2 up-regulation within the course of autoimmune encephalomyelitis correlates with T-lymphocyte activation Fulltext Access 11 Pages 2017
ROCK1/p53/NOXA signaling mediates cardiomyocyte apoptosis in response to high glucose in vitro and vivo Fulltext Access 11 Pages 2017
Pterostilbene attenuates high glucose-induced oxidative injury in hippocampal neuronal cells by activating nuclear factor erythroid 2-related factor 2 Fulltext Access 11 Pages 2017
Multiple pathways of SIRT6 at the crossroads in the control of longevity, cancer, and cardiovascular diseases Fulltext Access 11 Pages 2017
Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases Fulltext Access 11 Pages 2017
Regular articleRunning-induced memory enhancement correlates with the preservation of thin spines in the hippocampal area CA1 of old C57BL/6 mice Fulltext Access 11 Pages 2017
MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content Fulltext Access 11 Pages 2017
Hypoxia/reoxygenation-induced HMGB1 translocation and release promotes islet proinflammatory cytokine production and early islet graft failure through TLRs signaling Fulltext Access 11 Pages 2017
Preaged remodeling of myofibrillar cytoarchitecture in skeletal muscle expressing R349P mutant desmin Fulltext Access 11 Pages 2017
Nonamyloidogenic processing of amyloid beta precursor protein is associated with retinal function improvement in aging male APPswe/PS1ÎE9 mice Fulltext Access 11 Pages 2017
Polychlorinated biphenyls-153 induces metabolic dysfunction through activation of ROS/NF-κB signaling via downregulation of HNF1b Fulltext Access 11 Pages 2017
A capture method based on the VC1 domain reveals new binding properties of the human receptor for advanced glycation end products (RAGE) Fulltext Access 11 Pages 2017
Tert-butyl hydroperoxide (t-BHP) induced apoptosis and necroptosis in endothelial cells: Roles of NOX4 and mitochondrion Fulltext Access 11 Pages 2017
Dynamic range in BOLD modulation: lifespan aging trajectories and association with performance Fulltext Access 11 Pages 2017
Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes Fulltext Access 11 Pages 2017
Sequestration of polyunsaturated fatty acids in membrane phospholipids of Caenorhabditis elegans dauer larva attenuates eicosanoid biosynthesis for prolonged survival Fulltext Access 11 Pages 2017
Metabolomics analysis reveals that benzo[a]pyrene, a component of PM2.5, promotes pulmonary injury by modifying lipid metabolism in a phospholipase A2-dependent manner in vivo and in vitro Fulltext Access 11 Pages 2017
Low molar excess of 4-oxo-2-nonenal and 4-hydroxy-2-nonenal promote oligomerization of alpha-synuclein through different pathways Fulltext Access 11 Pages 2017
Cold atmospheric plasma restores tamoxifen sensitivity in resistant MCF-7 breast cancer cell Fulltext Access 11 Pages 2017
Mitochondrial aldehyde dehydrogenase-2 deficiency compromises therapeutic effect of ALDH bright cell on peripheral ischemia Fulltext Access 11 Pages 2017
The caspase-8/Bid/cytochrome c axis links signals from death receptors to mitochondrial reactive oxygen species production Fulltext Access 11 Pages 2017
Altered bioenergetics and enhanced resistance to oxidative stress in human retinal pigment epithelial cells from donors with age-related macular degeneration Fulltext Access 11 Pages 2017
4-hydroxynonenal protein adducts: Key mediator in Rett syndrome oxinflammation Fulltext Access 11 Pages 2017
Oxysterols and 4-hydroxy-2-nonenal contribute to atherosclerotic plaque destabilization Fulltext Access 11 Pages 2017
Adenosine A2 receptor activation ameliorates mitochondrial oxidative stress upon reperfusion through the posttranslational modification of NDUFV2 subunit of complex I in the heart Fulltext Access 11 Pages 2017
Administration of 5-methoxyindole-2-carboxylic acid that potentially targets mitochondrial dihydrolipoamide dehydrogenase confers cerebral preconditioning against ischemic stroke injury Fulltext Access 11 Pages 2017
Suppressed ubiquitination of Nrf2 by p47phox contributes to Nrf2 activation Fulltext Access 11 Pages 2017
Changes in Zn homeostasis during long term culture of primary endothelial cells and effects of Zn on endothelial cell senescence Fulltext Access 11 Pages 2017
Divergent effects of resistance training and anabolic steroid on the postsynaptic region of different skeletal muscles of aged rats Fulltext Access 11 Pages 2017
The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via CXCR1-dependent ROS accumulation and DNA damage and reinforces the destructive effect of these cells on homeostasis of intervertebral discs Fulltext Access 11 Pages 2017
TNFa knockdown in the retina promotes cone survival in a mouse model of autosomal dominant retinitis pigmentosa Fulltext Access 11 Pages 2017
Circ100284, via miR-217 regulation of EZH2, is involved in the arsenite-accelerated cell cycle of human keratinocytes in carcinogenesis Fulltext Access 11 Pages 2017
A new flavonoid glycoside (APG) isolated from Clematis tangutica attenuates myocardial ischemia/reperfusion injury via activating PKCε signaling Fulltext Access 11 Pages 2017
Aberrant base excision repair pathway of oxidatively damaged DNA: Implications for degenerative diseases Fulltext Access 12 Pages 2017
Elimination of dysfunctional mitochondria through mitophagy suppresses benzo[a]pyrene-induced apoptosis Fulltext Access 12 Pages 2017
Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1 Fulltext Access 12 Pages 2017
Regular articleDecline of prefrontal cortical-mediated executive functions but attenuated delay discounting in aged Fischer 344Â Ã brown Norway hybrid rats Fulltext Access 12 Pages 2017
Kalirin reduction rescues psychosis-associated behavioral deficits in APPswe/PSEN1dE9 transgenic mice Fulltext Access 12 Pages 2017
Regular articleThe expression and activity of KV3.4 channel subunits are precociously upregulated in astrocytes exposed to Aβ oligomers and in astrocytes of Alzheimer's disease Tg2576 mice Fulltext Access 12 Pages 2017
AlphaB-crystallin expression correlates with aging deficits in the peripheral nervous system Fulltext Access 12 Pages 2017
Early interleukin-6 enhances hepatic ketogenesis in APPSWE/PSEN1dE9 mice via 3-hydroxy-3-methylglutary-CoA synthase 2 signaling activation by p38/nuclear factor κB p65 Fulltext Access 12 Pages 2017
Preconditioning tDCS facilitates subsequent tDCS effect on skill acquisition in older adults Fulltext Access 12 Pages 2017
Hydrogen peroxide resistance in Strigomonas culicis: Effects on mitochondrial functionality and Aedes aegypti interaction Fulltext Access 12 Pages 2017
Aging-associated metabolic disorder induces Nox2 activation and oxidative damage of endothelial function Fulltext Access 12 Pages 2017
Kaempferol increases levels of coenzyme Q in kidney cells and serves as a biosynthetic ring precursor Fulltext Access 12 Pages 2017
Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease Fulltext Access 12 Pages 2017
Polyamine- and NADPH-dependent generation of ROS during Helicobacter pylori infection: A blessing in disguise Fulltext Access 12 Pages 2017
Original articleAbsence of DJ-1 causes age-related retinal abnormalities in association with increased oxidative stress Fulltext Access 12 Pages 2017
Hyper-activation of pp60Src limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injury Fulltext Access 12 Pages 2017
Intact mitochondrial Ca2+ uniport is essential for agonist-induced activation of endothelial nitric oxide synthase (eNOS) Fulltext Access 12 Pages 2017
Peroxiredoxin 2 regulates PGF2α-induced corpus luteum regression in mice by inhibiting ROS-dependent JNK activation Fulltext Access 12 Pages 2017