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Daneshyari Ageing Journas Latest Articles

Ageing Research Articles

Mesencephalic astrocyte-derived neurotrophic factor alleviated 6-OHDA-induced cell damage via ROS-AMPK/mTOR mediated autophagic inhibition
Fulltext Access 12 Pages 2017
Adiponectin attenuates NADPH oxidase-mediated oxidative stress and neuronal damage induced by cerebral ischemia-reperfusion injury
Fulltext Access 12 Pages 2017
Parkin elimination of mitochondria is important for maintenance of lens epithelial cell ROS levels and survival upon oxidative stress exposure
Fulltext Access 12 Pages 2017
miR-21-5p/203a-3p promote ox-LDL-induced endothelial cell senescence through down-regulation of mitochondrial fission protein Drp1
Fulltext Access 12 Pages 2017
Isoniazid inhibits human erythroid 5-aminolevulinate synthase: Molecular mechanism and tolerance study with four X-linked protoporphyria patients
Fulltext Access 12 Pages 2017
ReviewThe transcription factor carbohydrate-response element-binding protein (ChREBP): A possible link between metabolic disease and cancer
Fulltext Access 12 Pages 2017
MicroRNA-130b transcriptionally regulated by histone H3 deacetylation renders Akt ubiquitination and apoptosis resistance to 6-OHDA
Fulltext Access 12 Pages 2017
A novel mechanism of diabetic vascular endothelial dysfunction: Hypoadiponectinemia-induced NLRP3 inflammasome activation
Fulltext Access 12 Pages 2017
Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity
Fulltext Access 12 Pages 2017
Translational effects and coding potential of an upstream open reading frame associated with DOPA Responsive Dystonia
Fulltext Access 12 Pages 2017
Reciprocal regulation of eNOS, H2S and CO-synthesizing enzymes in human atheroma: Correlation with plaque stability and effects of simvastatin
Fulltext Access 12 Pages 2017
HPW-RX40 prevents human platelet activation by attenuating cell surface protein disulfide isomerases
Fulltext Access 12 Pages 2017
Oncogenic function of TUSC3 in non-small cell lung cancer is associated with Hedgehog signalling pathway
Fulltext Access 12 Pages 2017
C9ORF72 and parkinsonism: Weak link, innocent bystander, or central player in neurodegeneration?
Fulltext Access 12 Pages 2017
Delayed leukoencephalopathy after recanalized cardioembolic stroke: Two case reports
Fulltext Access 12 Pages 2017
CO-releasing molecules CORM2 attenuates angiotensin II-induced human aortic smooth muscle cell migration through inhibition of ROS/IL-6 generation and matrix metalloproteinases-9 expression
Fulltext Access 12 Pages 2017
Autophagy deficient keratinocytes display increased DNA damage, senescence and aberrant lipid composition after oxidative stress in vitro and in vivo
Fulltext Access 12 Pages 2017
The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo
Fulltext Access 12 Pages 2017
Ugonin U stimulates NLRP3 inflammasome activation and enhances inflammasome-mediated pathogen clearance
Fulltext Access 12 Pages 2017
Decreased neural precursor cell pool in NADPH oxidase 2-deficiency: From mouse brain to neural differentiation of patient derived iPSC
Fulltext Access 12 Pages 2017
Centenarians maintain miRNA biogenesis pathway while it is impaired in octogenarians
Fulltext Access 12 Pages 2017
Sex-specific and inter-individual differences in biomarkers of selenium status identified by a calibrated ELISA for selenoprotein P
Fulltext Access 12 Pages 2017
Hurst revisited: Are symptoms and signs of functional motor and sensory disorders “dependent on idea”?
Fulltext Access 12 Pages 2017
The mechanism of formation, structure and physiological relevance of covalent hemoglobin attachment to the erythrocyte membrane
Fulltext Access 12 Pages 2017
Mechanisms of myeloperoxidase catalyzed oxidation of H2S by H2O2 or O2 to produce potent protein Cys-polysulfide-inducing species
Fulltext Access 13 Pages 2017
Differential redox sensitivity of cathepsin B and L holds the key to autophagy-apoptosis interplay after Thioredoxin reductase inhibition in nutritionally stressed SH-SY5Y cells
Fulltext Access 13 Pages 2017
Parkinsonian-Pyramidal syndromes: A systematic review
Fulltext Access 13 Pages 2017
Circulating leptin and adiponectin concentrations in healthy exceptional longevity
Fulltext Access 13 Pages 2017
Novel MT-ND5 gene mutation identified in Leber's hereditary optic neuropathy patient using mitochondrial genome sequencing
Fulltext Access 13 Pages 2017
Xeroderma pigmentosum complementation group F: A rare cause of cerebellar ataxia with chorea
Fulltext Access 13 Pages 2017
Retroviral envelope proteins: Involvement in neuropathogenesis
Fulltext Access 13 Pages 2017
Polymyositis induced by PD-1 blockade in a patient in hepatitis B remission
Fulltext Access 13 Pages 2017
Klotho gene expression decreases in peripheral blood mononuclear cells (PBMCs) of patients with relapsing-remitting multiple sclerosis
Fulltext Access 13 Pages 2017
Thioredoxin (Trxo1) interacts with proliferating cell nuclear antigen (PCNA) and its overexpression affects the growth of tobacco cell culture
Fulltext Access 13 Pages 2017
Anti-NMDA receptor encephalitis due to large-cell neuroendocrine carcinoma of the uterus
Fulltext Access 13 Pages 2017
Nox2 contributes to hyperinsulinemia-induced redox imbalance and impaired vascular function
Fulltext Access 13 Pages 2017
Hormesis enables cells to handle accumulating toxic metabolites during increased energy flux
Fulltext Access 13 Pages 2017
Renal denervation attenuates hypertension and renal dysfunction in a model of cardiovascular and renal disease, which is associated with reduced NADPH and xanthine oxidase activity
Fulltext Access 13 Pages 2017
A review of redox signaling and the control of MAP kinase pathway in plants
Fulltext Access 13 Pages 2017
Degenerate cysteine patterns mediate two redox sensing mechanisms in the papillomavirus E7 oncoprotein
Fulltext Access 13 Pages 2017
Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease
Fulltext Access 13 Pages 2017
Deficiency in Duox2 activity alleviates ileitis in GPx1- and GPx2-knockout mice without affecting apoptosis incidence in the crypt epithelium
Fulltext Access 13 Pages 2017
Genetic disruption of NRF2 promotes the development of necroinflammation and liver fibrosis in a mouse model of HFE-hereditary hemochromatosis
Fulltext Access 13 Pages 2017
Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration
Fulltext Access 13 Pages 2017
Autophagy regulates turnover of lipid droplets via ROS-dependent Rab25 activation in hepatic stellate cell
Fulltext Access 13 Pages 2017
BID links ferroptosis to mitochondrial cell death pathways
Fulltext Access 13 Pages 2017
Zinc deficiency affects the STAT1/3 signaling pathways in part through redox-mediated mechanisms
Fulltext Access 13 Pages 2017
Nicotinamide nucleotide transhydrogenase (NNT) deficiency dysregulates mitochondrial retrograde signaling and impedes proliferation
Fulltext Access 13 Pages 2017
Hippocampal neurophysiology is modified by a disease-associated C-terminal fragment of tau protein
Fulltext Access 13 Pages 2017
Combined NADPH and the NOX inhibitor apocynin provides greater anti-inflammatory and neuroprotective effects in a mouse model of stroke
Fulltext Access 13 Pages 2017
Increasing GABA reverses age-related alterations in excitatory receptive fields and intensity coding of auditory midbrain neurons in aged mice
Fulltext Access 13 Pages 2017
Regular articleAltered protein glycosylation predicts Alzheimer's disease and modulates its pathology in disease model Drosophila
Fulltext Access 13 Pages 2017
Ataxia-telangiectasia (A-T): An emerging dimension of premature ageing
Fulltext Access 13 Pages 2017
Growth arrest and DNA damage-inducible 45α protects against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet
Fulltext Access 13 Pages 2017
Changes in podocyte TRPC channels evoked by plasma and sera from patients with recurrent FSGS and by putative glomerular permeability factors
Fulltext Access 13 Pages 2017
Cardiomyocyte-specific deletion of the G protein-coupled estrogen receptor (GPER) leads to left ventricular dysfunction and adverse remodeling: A sex-specific gene profiling analysis
Fulltext Access 13 Pages 2017
The clinical value of inflammatory biomarkers in coronary artery disease: PTX3 as a new inflammatory marker
Fulltext Access 13 Pages 2017
A summary of the Proceedings of the Thirteenth International Symposium on the Neurobiology and Neuroendocrinology of Aging, Bregenz, Austria July 17-22, 2016
Fulltext Access 13 Pages 2017
Ilex paraguariensis supplementation may be an effective nutritional approach to modulate oxidative stress during perimenopause
Fulltext Access 13 Pages 2017
Longevity in Calumma parsonii, the World's largest chameleon
Fulltext Access 13 Pages 2017
Redox imbalance due to the loss of mitochondrial NAD(P)-transhydrogenase markedly aggravates high fat diet-induced fatty liver disease in mice
Fulltext Access 13 Pages 2017
4-Hydroxynonenal metabolites and adducts in pre-carcinogenic conditions and cancer
Fulltext Access 13 Pages 2017
Opposite effects of catalase and MnSOD ectopic expression on stress induced defects and mortality in the desmin deficient cardiomyopathy model
Fulltext Access 13 Pages 2017
Vitamin E isoform γ-tocotrienol protects against emphysema in cigarette smoke-induced COPD
Fulltext Access 13 Pages 2017
EphB2 signaling-mediated Sirt3 expression reduces MSC senescence by maintaining mitochondrial ROS homeostasis
Fulltext Access 13 Pages 2017
Punicalagin, a PTP1B inhibitor, induces M2c phenotype polarization via up-regulation of HO-1 in murine macrophages
Fulltext Access 13 Pages 2017
Mechanistic and biological considerations of oxidatively damaged DNA for helicase-dependent pathways of nucleic acid metabolism
Fulltext Access 13 Pages 2017
Ptgr1 expression is regulated by NRF2 in rat hepatocarcinogenesis and promotes cell proliferation and resistance to oxidative stress
Fulltext Access 13 Pages 2017
Dapagliflozin, a selective SGLT2 Inhibitor, attenuated cardiac fibrosis by regulating the macrophage polarization via STAT3 signaling in infarcted rat hearts
Fulltext Access 13 Pages 2017
Lipid peroxidation in face of DNA damage, DNA repair and other cellular processes
Fulltext Access 13 Pages 2017
Protein S-glutathionylation alters superoxide/hydrogen peroxide emission from pyruvate dehydrogenase complex
Fulltext Access 13 Pages 2017
High concentration of branched-chain amino acids promotes oxidative stress, inflammation and migration of human peripheral blood mononuclear cells via mTORC1 activation
Fulltext Access 13 Pages 2017
Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis
Fulltext Access 14 Pages 2017
Regular articleAmyloid-β42 clearance and neuroprotection mediated by X-box binding protein 1 signaling decline with aging in the Drosophila brain
Fulltext Access 14 Pages 2017
Are microRNAs true sensors of ageing and cellular senescence?
Fulltext Access 14 Pages 2017
ReviewThe emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans
Fulltext Access 14 Pages 2017
One-year follow-up of clinical, metabolic and oxidative stress profile of morbid obese patients after laparoscopic sleeve gastrectomy. 8-oxo-dG as a clinical marker
Fulltext Access 14 Pages 2017
'Tagging' along memories in aging: Synaptic tagging and capture mechanisms in the aged hippocampus
Fulltext Access 14 Pages 2017
DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells-Implications for age-related macular degeneration (AMD)
Fulltext Access 14 Pages 2017
Phytochemical-induced nucleolar stress results in the inhibition of breast cancer cell proliferation
Fulltext Access 14 Pages 2017
Clinical validity of increased cortical uptake of amyloid ligands on PET as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework
Fulltext Access 14 Pages 2017
Regular articleRelative cortico-subcortical shift in brain activity but preserved training-induced neural modulation in older adults during bimanual motor learning
Fulltext Access 14 Pages 2017
A cross-sectional comparison of ethanol-related cytokine expression in the hippocampus of young and aged Fischer 344 rats
Fulltext Access 14 Pages 2017
A randomized trial of relamorelin for constipation in Parkinson's disease (MOVE-PD): Trial results and lessons learned
Fulltext Access 14 Pages 2017
MiR-525-3p mediates antiviral defense to rotavirus infection by targeting nonstructural protein 1
Fulltext Access 14 Pages 2017
The Zn2+-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl− absorption, via basolateral KCC1, and reduces fluid loss
Fulltext Access 14 Pages 2017
Apixaban for the treatment of cerebral venous thrombosis: A case series
Fulltext Access 14 Pages 2017
Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells
Fulltext Access 14 Pages 2017
Characterization of stem cell-derived liver and intestinal organoids as a model system to study nuclear receptor biology
Fulltext Access 14 Pages 2017
Association of SAA gene polymorphism with ischemic stroke in northern Chinese Han population
Fulltext Access 14 Pages 2017
Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration
Fulltext Access 14 Pages 2017
Head CT findings at a public hospital in rural Haiti
Fulltext Access 14 Pages 2017
Wogonin, a plant derived small molecule, exerts potent anti-inflammatory and chondroprotective effects through the activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes
Fulltext Access 14 Pages 2017
Decoding NADPH oxidase 4 expression in human tumors
Fulltext Access 14 Pages 2017
Rapid generation of hydrogen peroxide contributes to the complex cell death induction by the angucycline antibiotic landomycin E
Fulltext Access 14 Pages 2017
Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma
Fulltext Access 14 Pages 2017
Cysteine-rich whey protein isolate (Immunocal®) ameliorates deficits in the GFAP.HMOX1 mouse model of schizophrenia
Fulltext Access 14 Pages 2017
SIOG 2017 - Invited Speaker Biographies
Fulltext Access 14 Pages 2017
Glucose-6-phosphate dehydrogenase and Trypanothione reductase interaction protects Leishmania donovani from metalloid mediated oxidative stress
Fulltext Access 14 Pages 2017
Sensing of dangerous DNA
Fulltext Access 14 Pages 2017
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