The cytoplasmic thioredoxin system in Caenorhabditis elegans affords protection from methylmercury in an age-specific manner Fulltext Access 39 Pages 2018
Molecular characterization, tissue distribution, localization and mRNA expression of the bucky ball gene in the Dabry's sturgeon (Acipenser dabryanus) during oogenesis Fulltext Access 39 Pages 2018
Methylated flavonoids as anti-seizure agents: Naringenin 4â²,7-dimethyl ether attenuates epileptic seizures in zebrafish and mouse models Fulltext Access 39 Pages 2018
Inhibition of α2C-adrenoceptors ameliorates cisplatin-induced acute renal failure in rats Fulltext Access 39 Pages 2018
Resveratrol activation of AMPK-dependent pathways is neuroprotective in human neural stem cells against amyloid-beta-induced inflammation and oxidative stress Fulltext Access 39 Pages 2018
Alterations in the E3 ligases Parkin and CHIP result in unique metabolic signaling defects and mitochondrial quality control issues Fulltext Access 39 Pages 2018
Peripheral GABAA receptor-mediated signaling facilitates persistent inflammatory hypersensitivity Fulltext Access 40 Pages 2018
Insulin-mediated synaptic plasticity in the CNS: Anatomical, functional and temporal contexts Fulltext Access 40 Pages 2018
Hypoxia-induced upregulation of Orai1 drives colon cancer invasiveness and angiogenesis Fulltext Access 40 Pages 2018
Intracellular emetic signaling evoked by the L-type Ca2+ channel agonist FPL64176 in the least shrew (Cryptotis parva) Fulltext Access 40 Pages 2018
Comparative proteomics reveals the neurotoxicity mechanism of ER stressors tunicamycin and dithiothreitol Fulltext Access 40 Pages 2018
3,4-Methylenedioxymethamphetamine, mephedrone, and β-phenylethylamine release dopamine from the cytoplasm by means of transporters and keep the concentration high and constant by blocking reuptake Fulltext Access 40 Pages 2018
Novel oxindole derivatives prevent oxidative stress-induced cell death in mouse hippocampal HT22â¯cells Fulltext Access 40 Pages 2018
Periaqueductal gray glutamatergic, cannabinoid and vanilloid receptor interplay in defensive behavior and aversive memory formation Fulltext Access 40 Pages 2018
Downregulation of estrogen-related receptor alpha inhibits human cutaneous squamous cell carcinoma cell proliferation and migration by regulating EMT via fibronectin and STAT3 signaling pathways Fulltext Access 40 Pages 2018
Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace Fulltext Access 40 Pages 2018
Conditional inactivation of Npy1r gene in mice induces behavioural inflexibility and orbitofrontal cortex hyperactivity that are reversed by escitalopram Fulltext Access 40 Pages 2018
Brain disposition, metabolism and behavioral effects of the synthetic opioid AH-7921 in rats Fulltext Access 40 Pages 2018
Protective effects of pituitary adenylate cyclase activating polypeptide against neurotoxic agents Fulltext Access 40 Pages 2018
“Ecstasy” to addiction: Mechanisms and reinforcing effects of three synthetic cathinone analogs of MDMA Fulltext Access 40 Pages 2018
Adenoviral vector-induced silencing of RGMa attenuates blood-brain barrier dysfunction in a rat model of MCAO/reperfusion Fulltext Access 40 Pages 2018
In vivo assessment of neurological channelopathies: Application of peripheral nerve excitability studies Fulltext Access 40 Pages 2018
Neural progenitors derived from Tuberous Sclerosis Complex patients exhibit attenuated PI3K/AKT signaling and delayed neuronal differentiation Fulltext Access 40 Pages 2018
GLP-1 receptor agonists downregulate aberrant GnT-III expression in Alzheimer's disease models through the Akt/GSK-3β/β-catenin signaling Fulltext Access 40 Pages 2018
Bioisosteres of ethyl 8-ethynyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo [1,5-a][1,4]diazepine-3-carboxylate (HZ-166) as novel alpha 2,3 selective potentiators of GABAA receptors: Improved bioavailability enhances anticonvulsant efficacy Fulltext Access 40 Pages 2018
The investigation of the pyrethroid insecticide lambda-cyhalothrin (LCT)-affected Ca2+ homeostasis and -activated Ca2+-associated mitochondrial apoptotic pathway in normal human astrocytes: The evaluation of protective effects of BAPTA-AM (a selective Ca2 Fulltext Access 40 Pages 2018
A novel selective MAO-B inhibitor with neuroprotective and anti-Parkinsonian properties Fulltext Access 40 Pages 2018
Paeonol promotes hippocampal synaptic transmission: The role of the Kv2.1 potassium channel Fulltext Access 40 Pages 2018
Varenicline reduces DNA damage, tau mislocalization and post surgical cognitive impairment in aged mice Fulltext Access 40 Pages 2018
2',3-dihydroxy-5-methoxybiphenyl suppresses fMLP-induced superoxide anion production and cathepsin G release by targeting the β-subunit of G-protein in human neutrophils Fulltext Access 40 Pages 2018
Cyto-nuclear shuttling of afadin is required for rapid estradiol-mediated modifications of histone H3 Fulltext Access 40 Pages 2018
Assessment of metal concentrations in the SOD1G93A mouse model of amyotrophic lateral sclerosis and its potential role in muscular denervation, with particular focus on muscle tissue Fulltext Access 40 Pages 2018
Fast and slow-twitching muscles are differentially affected by reduced cholinergic transmission in mice deficient for VAChT: A mouse model for congenital myasthenia Fulltext Access 40 Pages 2018
Salidroside improves brain ischemic injury by activating PI3K/Akt pathway and reduces complications induced by delayed tPA treatment Fulltext Access 40 Pages 2018
Ouabain increases neuronal branching in hippocampus and improves spatial memory Fulltext Access 40 Pages 2018
Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation Fulltext Access 40 Pages 2018
Cholecalciferol counteracts depressive-like behavior and oxidative stress induced by repeated corticosterone treatment in mice Fulltext Access 40 Pages 2018
α1A-Adrenoceptors, but not α1B- or α1D-adrenoceptors, contribute to enhanced contractile response to phenylephrine in cooling conditions in the rat tail artery Fulltext Access 40 Pages 2018
Galantamine attenuates N,N-dimethyl hydrazine induced neoplastic colon damage by inhibiting acetylcholinesterase and bimodal regulation of nicotinic cholinergic neurotransmission Fulltext Access 40 Pages 2018
The secretome of adipose-derived mesenchymal stem cells protects SH-SY5Y cells from arsenic-induced toxicity, independent of a neuron-like differentiation mechanism Fulltext Access 41 Pages 2018
Salusin-α attenuates hepatic steatosis and atherosclerosis in high fat diet-fed low density lipoprotein receptor deficient mice Fulltext Access 41 Pages 2018
Colitis-induced alterations in response properties of visceral nociceptive neurons in the rat caudal medulla oblongata and their modulation by 5-HT3 receptor blockade Fulltext Access 41 Pages 2018
SKA-31, an activator of endothelial Ca2+-activated K+ channels evokes robust vasodilation in rat mesenteric arteries Fulltext Access 41 Pages 2018
Anti-cancer activity of a new dihydropyridine derivative, VdiE-2N, in head and neck squamous cell carcinoma Fulltext Access 41 Pages 2018
Hydroxysafflor yellow a protects brain microvascular endothelial cells against oxygen glucose deprivation/reoxygenation injury: Involvement of inhibiting autophagy via class I PI3K/Akt/mTOR signaling pathway Fulltext Access 41 Pages 2018
Methamphetamine-induced impulsivity during chronic methamphetamine treatment in rats: Effects of the TAAR 1 agonist RO5263397 Fulltext Access 41 Pages 2018
Allosteric interactions between GABAB1 subunits control orthosteric binding sites occupancy within GABAB oligomers Fulltext Access 41 Pages 2018
α-(phenylselanyl) acetophenone abolishes acute restraint stress induced-comorbid pain, depression and anxiety-related behaviors in mice Fulltext Access 41 Pages 2018
Occupancy of adenosine A2A receptors by istradefylline in patients with Parkinson's disease using 11C-preladenant PET Fulltext Access 41 Pages 2018
Age-dependent and region-specific alteration of parvalbumin neurons and perineuronal nets in the mouse cerebral cortex Fulltext Access 41 Pages 2018
Species specificity of rat and human α7 nicotinic acetylcholine receptors towards different classes of peptide and protein antagonists Fulltext Access 41 Pages 2018
Self-administration of the synthetic cathinone MDPV enhances reward function via a nicotinic receptor dependent mechanism Fulltext Access 41 Pages 2018
A screening campaign in sea urchin egg homogenate as a platform for discovering modulators of NAADP-dependent Ca2+ signaling in human cells Fulltext Access 41 Pages 2018
Positive allosteric modulation of M1 and M4 muscarinic receptors as potential therapeutic treatments for schizophrenia Fulltext Access 41 Pages 2018
NAADP-dependent Ca2+ signaling regulates Middle East respiratory syndrome-coronavirus pseudovirus translocation through the endolysosomal system Fulltext Access 41 Pages 2018
[D-Leu-4]-OB3 and MA-[D-Leu-4]-OB3, small molecule synthetic peptide leptin mimetics, improve glycemic control in diet-induced obese (DIO) mice Fulltext Access 41 Pages 2018
Intoxication from the novel synthetic cannabinoids AB-PINACA and ADB-PINACA: A case series and review of the literature Fulltext Access 41 Pages 2018
Pituitary adenylate cyclase-activating polypeptide (PACAP) signaling in the prefrontal cortex modulates cued fear learning, but not spatial working memory, in female rats Fulltext Access 41 Pages 2018
AMPA receptor GluA1 Ser831 phosphorylation is critical for nitroglycerin-induced migraine-like pain Fulltext Access 41 Pages 2018
A hypothalamo-midbrain-medullary pathway involved in the inhibition of the respiratory chemoreflex response induced by potassium cyanide in rodents Fulltext Access 42 Pages 2018
Nicotinamide prevents sweet beverage-induced hepatic steatosis in rats by regulating the G6PD, NADPH/NADP+ and GSH/GSSG ratios and reducing oxidative and inflammatory stress Fulltext Access 42 Pages 2018
Treatment with corn oil improves neurogenesis and cognitive performance in the Ts65Dn mouse model of Down syndrome Fulltext Access 42 Pages 2018
Cardiovascular pressor effects of orexins in the dorsomedial hypothalamus Fulltext Access 42 Pages 2018
Neuroprotective effect of an Nrf2-ARE activator identified from a chemical library on dopaminergic neurons Fulltext Access 42 Pages 2018
A pentacyclic triterpene derivative possessing polyhydroxyl ring A suppresses growth of HeLa cells by reactive oxygen species-dependent NF-κB pathway Fulltext Access 42 Pages 2018
Zaprinast diminished pain and enhanced opioid analgesia in a rat neuropathic pain model Fulltext Access 42 Pages 2018
Role of hippocampal 5-HT1A receptors in the antidepressant-like phenotype of mice expressing RGS-insensitive Gαi2 protein Fulltext Access 42 Pages 2018
Impaired oligodendrogenesis and myelination by elevated S100B levels during neurodevelopment Fulltext Access 42 Pages 2018
Ras inhibitor S-trans, trans-farnesylthiosalicylic acid enhances spatial memory and hippocampal long-term potentiation via up-regulation of NMDA receptor Fulltext Access 42 Pages 2018
Targeting the Dvl-1/β-arrestin2/JNK3 interaction disrupts Wnt5a-JNK3 signaling and protects hippocampal CA1 neurons during cerebral ischemia reperfusion Fulltext Access 42 Pages 2018
Acidosis mediates recurrent hypoglycemia-induced increase in ischemic brain injury in treated diabetic rats Fulltext Access 42 Pages 2018
Intracerebroventricular streptozotocin impairs adult neurogenesis and cognitive functions via regulating neuroinflammation and insulin signaling in adult rats Fulltext Access 42 Pages 2018
Kv3 K+ currents contribute to spike-timing in dorsal cochlear nucleus principal cells Fulltext Access 42 Pages 2018
Autoantibody-mediated diseases of the CNS: Structure, dysfunction and therapy Fulltext Access 42 Pages 2018
Adipose-derived stem cells decrease pain in a rat model of oxaliplatin-induced neuropathy: Role of VEGF-A modulation Fulltext Access 42 Pages 2018
Low doses of prenatal ethanol exposure and maternal separation alter HPA axis function and ethanol consumption in adult male rats Fulltext Access 42 Pages 2018
JNK1 inhibition by Licochalcone A leads to neuronal protection against excitotoxic insults derived of kainic acid Fulltext Access 42 Pages 2018
Activation of ERK/CREB pathway in noradrenergic neurons contributes to hypernociceptive phenotype in H4 receptor knockout mice after nerve injury Fulltext Access 42 Pages 2018
Depressed mitochondrial function and electron transport Complex II-mediated H2O2 production in the cortex of type 1 diabetic rodents Fulltext Access 42 Pages 2018
Lixisenatide ameliorates cerebral ischemia-reperfusion injury via GLP-1 receptor dependent/independent pathways Fulltext Access 42 Pages 2018
Physiological signature of a novel potentiator of AMPA receptor signalling Fulltext Access 42 Pages 2018
Histone deacetylases (HDACs) as therapeutic target for depressive disorders Fulltext Access 42 Pages 2018
3-(4-Chlorophenylselanyl)-1-methyl-1H-indole, a new selenium compound elicits an antinociceptive and anti-inflammatory effect in mice Fulltext Access 42 Pages 2018
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ1-42-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways Fulltext Access 43 Pages 2018
Agmatine potentiates neuroprotective effects of subthreshold concentrations of ketamine via mTOR/S6 kinase signaling pathway Fulltext Access 43 Pages 2018
Schwann cell lamellipodia regulate cell-cell interactions and phagocytosis Fulltext Access 43 Pages 2018
N-propyl-2,2-diphenyl-2-hydroxyacetamide, a novel α-hydroxyamide with anticonvulsant, anxiolytic and antidepressant-like effects that inhibits voltage-gated sodium channels Fulltext Access 43 Pages 2018
Class I histone deacetylases in retinal progenitors and differentiating ganglion cells Fulltext Access 43 Pages 2018
Adolescent chronic variable social stress influences exploratory behavior and nicotine responses in male, but not female, BALB/cJ mice Fulltext Access 43 Pages 2018
Ozone protects the rat lung from ischemia-reperfusion injury by attenuating NLRP3-mediated inflammation, enhancing Nrf2 antioxidant activity and inhibiting apoptosis Fulltext Access 43 Pages 2018
Conflicting roles of 20-HETE in hypertension and renal end organ damage Fulltext Access 43 Pages 2018
Dopaminergic and serotonergic mechanisms in the modulation of pain: In vivo studies in human brain Fulltext Access 43 Pages 2018
Treatments for diabetes mellitus type II: New perspectives regarding the possible role of calcium and cAMP interaction Fulltext Access 43 Pages 2018
Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling Fulltext Access 43 Pages 2018