Nebivolol prevents ethanol-induced reactive oxygen species generation and lipoperoxidation in the rat kidney by regulating NADPH oxidase activation and expression Fulltext Access 8 Pages 2017
Cyclic AMP (cAMP) confers drug resistance against DNA damaging agents via PKAIA in CML cells Fulltext Access 8 Pages 2017
Blockade of patch-based μ opioid receptors in the striatum attenuates methamphetamine-induced conditioned place preference and reduces activation of the patch compartment Fulltext Access 8 Pages 2017
Amitriptyline down-regulates coenzyme Q10 biosynthesis in lung cancer cells Fulltext Access 8 Pages 2017
SIRT2 mediated antitumor effects of shikonin on metastatic colorectal cancer Fulltext Access 8 Pages 2017
Topical ocular treatment with monoclonal antibody Fab fragments targeting Japanese cedar pollen Cry j 1 inhibits Japanese cedar pollen-induced allergic conjunctivitis in mice Fulltext Access 8 Pages 2017
7-cyclopentyl-5-(4-phenoxyphenyl)â7H-pyrrolo[2,3-d] pyrimidin-4-ylamine inhibits the proliferation and migration of vascular smooth muscle cells by suppressing ERK and Akt pathways Fulltext Access 8 Pages 2017
Involvement of arterial baroreflex and nicotinic acetylcholine receptor α7 subunit pathway in the protection of metformin against stroke in stroke-prone spontaneously hypertensive rats Fulltext Access 8 Pages 2017
Loop-F of the α-subunit determines the pharmacologic profile of novel competitive inhibitors of GABAA receptors Fulltext Access 8 Pages 2017
12-Chloracetyl-PPD, a novel dammarane derivative, shows anti-cancer activity via delay the progression of cell cycle G2/M phase and reactive oxygen species-mediate cell apoptosis Fulltext Access 8 Pages 2017
Involvement of BDNF/TrkB signaling in the effect of diphenyl diselenide on motor function in a Parkinson's disease rat model Fulltext Access 8 Pages 2017
Rhinacanthin-C enhances doxorubicin cytotoxicity via inhibiting the functions of P-glycoprotein and MRP2 in breast cancer cells Fulltext Access 8 Pages 2017
Tetradecanol reduces EL-4 T cell growth by the down regulation of NF-κB mediated IL-2 secretion Fulltext Access 8 Pages 2017
Decrease of high voltage Ca2+ currents in the dentate gyrus granule cells by entorhinal amyloidopathy is reversed by calcium channel blockade Fulltext Access 8 Pages 2017
Inhibition of estrogen related receptor α attenuates vascular smooth muscle cell proliferation and migration by regulating RhoA/p27Kip1 and β-Catenin/Wnt4 signaling pathway Fulltext Access 8 Pages 2017
Inositol hexaphosphate suppresses colorectal cancer cell proliferation via the Akt/GSK-3β/β-catenin signaling cascade in a 1,2-dimethylhydrazine-induced rat model Fulltext Access 8 Pages 2017
The enhancement of TXA2 receptors-mediated contractile response in intrarenal artery dysfunction in type 2 diabetic mice Fulltext Access 8 Pages 2017
Evaluation of the CART peptide expression in morphine sensitization in male rats Fulltext Access 8 Pages 2017
Recombinant Newcastle disease virus expressing human TRAIL as a potential candidate for hepatoma therapy Fulltext Access 8 Pages 2017
Chemical inhibitors of c-Met receptor tyrosine kinase stimulate osteoblast differentiation and bone regeneration Fulltext Access 8 Pages 2017
Effects of bilobalide, ginkgolide B and picrotoxinin on GABAA receptor modulation by structurally diverse positive modulators Fulltext Access 8 Pages 2017
Protective effects of fluoroquinolones on UV-induced damage of cultured ocular cell lines Fulltext Access 8 Pages 2017
Chloroquine blocks the Kir4.1 channels by an open-pore blocking mechanism Fulltext Access 8 Pages 2017
The signalling mechanisms of a novel mitochondrial complex I inhibitor prevent lipid accumulation and attenuate TNF-α-induced insulin resistance in vitro Fulltext Access 8 Pages 2017
Inhibition of osteoporosis by the αvβ3 integrin antagonist of rhodostomin variants Fulltext Access 8 Pages 2017
Anticancer effect and enhancement of therapeutic potential of Vincristine by extract from aerial parts of Juniperus excelsa on pre-B acute lymphoblastic leukemia cell lines Fulltext Access 8 Pages 2017
Involvement of nitrergic system in anticonvulsant effect of zolpidem in lithium-pilocarpine induced status epilepticus: Evaluation of iNOS and COX-2 genes expression Fulltext Access 8 Pages 2017
Ketamine and aminoguanidine differentially affect Bdnf and Mtor gene expression in the prefrontal cortex of adult male rats Fulltext Access 8 Pages 2017
Protective effect of cinnamaldehyde against glutamate-induced oxidative stress and apoptosis in PC12 cells Fulltext Access 8 Pages 2017
Dose-dependent S-allyl cysteine ameliorates multiple sclerosis disease-related pathology by reducing oxidative stress and biomarkers of dysbiosis in experimental autoimmune encephalomyelitis Fulltext Access 8 Pages 2017
N-(2-methoxyphenyl) benzenesulfonamide, a novel regulator of neuronal G protein-gated inward rectifier K+ channels Fulltext Access 8 Pages 2017
Oridonin induces G2/M cell cycle arrest and apoptosis in human oral squamous cell carcinoma Fulltext Access 8 Pages 2017
A549 cells as a model to study endogenous LPA1 receptor signaling and regulation Fulltext Access 8 Pages 2017
20(S)-Ginsenoside Rh2 suppresses proliferation and migration of hepatocellular carcinoma cells by targeting EZH2 to regulate CDKN2A-2B gene cluster transcription Fulltext Access 8 Pages 2017
Pharmacological synergism of 2,2-dichloroacetophenone and EGFR-TKi to overcome TKi-induced resistance in NSCLC cells Fulltext Access 8 Pages 2017
Examining the temporo-mandibular joint from a biotensegrity perspective: A change in thinking Fulltext Access 8 Pages 2017
Modulation of HMG-CoA reductase and glutathione-linked enzymes and protection against pro-oxidant induced oxidative damage in colon (Caco-2) cells and rat colon homogenates by phenolic extracts from Shaddock (Citrus maxima) peels Fulltext Access 8 Pages 2017
Design and drug-like properties of new 5-methoxysalicylaldehyde based hydrazones with anti-breast cancer activity Fulltext Access 8 Pages 2017
An apple oligogalactan enhances the growth inhibitory effect of 5-fluorouracil on colorectal cancer Fulltext Access 8 Pages 2017
Alpha 2,3- and alpha 2,6-sialylation of human skim milk glycoproteins during milk maturation Fulltext Access 8 Pages 2017
Ameliorating effect of Curculigo orchoides on chromium(VI) induced oxidative stress via, modulation of cytokines, transcription factors and apoptotic genes Fulltext Access 8 Pages 2017
Effects of γ-radiation on cell growth, cell cycle and promoter methylation of 22 cell cycle genes in the 1321NI astrocytoma cell line Fulltext Access 8 Pages 2017
Tangeretin alters neuronal apoptosis and ameliorates the severity of seizures in experimental epilepsy-induced rats by modulating apoptotic protein expressions, regulating matrix metalloproteinases, and activating the PI3K/Akt cell survival pathway Fulltext Access 8 Pages 2017
A glycine transporter 2-Cre knock-in mouse line for glycinergic neuron-specific gene manipulation Fulltext Access 8 Pages 2017
Pharmacological effects of a recombinant hPTH(1â34) derived peptide on ovariectomized rats Fulltext Access 8 Pages 2017
Cinobufagin induces apoptosis of osteosarcoma cells through inactivation of Notch signaling Fulltext Access 8 Pages 2017
Cardamonin (2â²,4â²-dihydroxy-6â²-methoxychalcone) isolated from Boesenbergia rotunda (L.) Mansf. inhibits CFA-induced rheumatoid arthritis in rats Fulltext Access 8 Pages 2017
Canagliflozin, a sodium glucose cotransporter 2 inhibitor, attenuates obesity-induced inflammation in the nodose ganglion, hypothalamus, and skeletal muscle of mice Fulltext Access 8 Pages 2017
Caffeic acid phenethyl ester attenuates lipopolysaccharide-stimulated proinflammatory responses in human gingival fibroblasts via NF-κB and PI3K/Akt signaling pathway Fulltext Access 8 Pages 2017
In vivo and vitro characterization of the effects of kisspeptin-13, endogenous ligands for GPR54, on mouse gastrointestinal motility Fulltext Access 8 Pages 2017
Original articleNrf2 and NF-κB modulation by Plumbagin attenuates functional, behavioural and biochemical deficits in rat model of neuropathic pain Fulltext Access 8 Pages 2017
ReviewFrom mucolipidosis type IV to Ebola: TRPML and two-pore channels at the crossroads of endo-lysosomal trafficking and disease Fulltext Access 8 Pages 2017
Original articleAntinociceptive tolerance to NSAIDs in the rat formalin test is mediated by the opioid mechanism Fulltext Access 8 Pages 2017
Original articleSelective agonism of mGlu8 receptors by (S)-3,4-dicarboxyphenylglycine does not affect sleep stages in the rat Fulltext Access 8 Pages 2017
Original articleInfluence of genetic variants of CYP2D6, CYP2C9, CYP2C19 and CYP3A4 on antiepileptic drug metabolism in pediatric patients with refractory epilepsy Fulltext Access 8 Pages 2017
CB-1R and GLP-1R gene expressions and oxidative stress in the liver of diabetic rats treated with sitagliptin Fulltext Access 8 Pages 2017
Original articleThe selective estrogen receptor modulators (SERMs) raloxifene and tamoxifen improve ANP levels and decrease nuclear translocation of NF-kB in estrogen-deficient rats Fulltext Access 8 Pages 2017
N-Acetylcysteine-induced vasodilatation is modulated by KATP channels, Na+/K+-ATPase activity and intracellular calcium concentration: An in vitro study Fulltext Access 8 Pages 2017
Original articleEvaluation of ADMA, carbonyl groups, CAT and NKA in depressed patients with and without posttraumatic stress disorder Fulltext Access 8 Pages 2017
Original articleTranscranial direct current stimulation (tDCS) and its influence on analgesics effectiveness in patients suffering from migraine headache Fulltext Access 8 Pages 2017
Original articleShort-term exposure of erythropoietin impairs endothelial function through inhibition of nitric oxide production and eNOS mRNA expression in the rat pulmonary artery Fulltext Access 8 Pages 2017
Semi-automated program for analysis of local Ca2+ spark release with application for classification of heart cell type Fulltext Access 8 Pages 2017
Original articleEffects of fenoterol on the skeletal system depend on the androgen level Fulltext Access 8 Pages 2017
Original articleOmega-3 polyunsaturated fatty acids improve the antioxidative defense in rat astrocytes via an Nrf2-dependent mechanism Fulltext Access 8 Pages 2017
Original articleSpinal 5-HT4 and 5-HT6 receptors contribute to the maintenance of neuropathic pain in rats Fulltext Access 8 Pages 2017
Glucagon-like peptide-1 (GLP-1) increases in plasma and colon tissue prior to estrus and circulating levels change with increasing age in reproductively competent Wistar rats Fulltext Access 8 Pages 2017
Region-specific bioconversion of dynorphin neuropeptide detected by in situ histochemistry and MALDI imaging mass spectrometry Fulltext Access 8 Pages 2017
Changes in [3H]-ouabain and [3H]-neurotensin binding to rat cerebral cortex membranes after administration of antipsychotic drugs haloperidol and clozapine Fulltext Access 8 Pages 2017
Functional interaction between BDNF and mGluR II in vitro: BDNF down-regulated mGluR II gene expression and an mGluR II agonist enhanced BDNF-induced BDNF gene expression in rat cerebral cortical neurons Fulltext Access 8 Pages 2017
The efficacy of Dynorphin fragments at the κ, μ and δ opioid receptor in transfected HEK cells and in an animal model of unilateral peripheral inflammation Fulltext Access 8 Pages 2017
Feeding recombinant E. coli with GST-mBmKTX fusion protein increases the fecundity and lifespan of Caenorhabditis elegans Fulltext Access 8 Pages 2017
Research PaperSynthesis and activity of opioid peptidomimetics with β2- and β3-amino acids Fulltext Access 8 Pages 2017
Cathelicidins display conserved direct antiviral activity towards rhinovirus Fulltext Access 8 Pages 2017
Urothelial acetylcholine involvement in ATP-induced contractile responses of the rat urinary bladder Fulltext Access 8 Pages 2017
Effect of D-Ala2GIP, a stable GIP receptor agonist on MPTP-induced neuronal impairments in mice Fulltext Access 8 Pages 2017
Licocoumarone isolated from Glycyrrhiza uralensis selectively alters LPS-induced inflammatory responses in RAW 264.7 macrophages Fulltext Access 8 Pages 2017
JTE-852, a novel spleen tyrosine kinase inhibitor, blocks mediator secretion from mast cells with immunoglobulin E crosslinking Fulltext Access 8 Pages 2017
B7-33 replicates the vasoprotective functions of human relaxin-2 (serelaxin) Fulltext Access 8 Pages 2017
Trans-4-methoxy-β-nitrostyrene relaxes rat thoracic aorta through a sGC-dependent pathway Fulltext Access 8 Pages 2017
(-)-Terpinen-4-ol changes intracellular Ca2+ handling and induces pacing disturbance in rat hearts Fulltext Access 8 Pages 2017
Muscarinic receptor mediated signaling pathways in hepatocytes from CCL4 - induced liver fibrotic rat Fulltext Access 8 Pages 2017
Antidiabetic, antidyslipidemic and toxicity profile of ENV-2: A potent pyrazole derivative against diabetes and related diseases Fulltext Access 8 Pages 2017
JTP-117968, a novel selective glucocorticoid receptor modulator, exhibits improved transrepression/transactivation dissociation Fulltext Access 8 Pages 2017
Phenylmethimazole and a thiazole derivative of phenylmethimazole inhibit IL-6 expression by triple negative breast cancer cells Fulltext Access 8 Pages 2017
Guggulsterone sensitized drug-resistant human hepatocarcinoma cells to doxorubicin through a Cox-2/P-gp dependent pathway Fulltext Access 8 Pages 2017
Differential expression of glucagon-like peptide-2 (GLP-2) is involved in pancreatic islet cell adaptations to stress and beta-cell survival Fulltext Access 8 Pages 2017
A brain-targeted ampakine compound protects against opioid-induced respiratory depression Fulltext Access 8 Pages 2017
RP5063, a novel, multimodal, serotonin receptor modulator, prevents monocrotaline-induced pulmonary arterial hypertension in rats Fulltext Access 8 Pages 2017
Short communicationDifferential regulation of NM23-H1 under hypoxic and serum starvation conditions in metastatic cancer cells and its implication in EMT Fulltext Access 8 Pages 2017
Research paperEndosome to trans-Golgi network transport of Proprotein Convertase 7 is mediated by a cluster of basic amino acids and palmitoylated cysteines Fulltext Access 8 Pages 2017
ReviewCab45-Unraveling key features of a novel secretory cargo sorter at the trans-Golgi network Fulltext Access 8 Pages 2017
Research paperResveratrol promotes human embryonic stem cells self-renewal by targeting SIRT1-ERK signaling pathway Fulltext Access 8 Pages 2017
Research articleFerulic acid promotes osteogenesis of bone marrow-derived mesenchymal stem cells by inhibiting microRNA-340 to induce β-catenin expression through hypoxia Fulltext Access 8 Pages 2017
TRPP2 ion channels: Critical regulators of organ morphogenesis in health and disease Fulltext Access 8 Pages 2017
C1q/tumor necrosis factor-related protein-3 enhances the contractility of cardiomyocyte by increasing calcium sensitivity Fulltext Access 8 Pages 2017