Aquaporin-4 deficiency facilitates fear memory extinction in the hippocampus through excessive activation of extrasynaptic GluN2B-containing NMDA receptors Fulltext Access 11 Pages 2017
In vivo efficiency of the collagen coated nanofibrous scaffold and their effect on growth factors and pro-inflammatory cytokines in wound healing Fulltext Access 11 Pages 2017
Kynurenine pathway metabolism and immune activation: Peripheral measurements in psychiatric and co-morbid conditions Fulltext Access 11 Pages 2017
L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences Fulltext Access 11 Pages 2017
Oleuropein improves mitochondrial function to attenuate oxidative stress by activating the Nrf2 pathway in the hypothalamic paraventricular nucleus of spontaneously hypertensive rats Fulltext Access 11 Pages 2017
PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of microRNA-181a Fulltext Access 11 Pages 2017
Type-7 metabotropic glutamate receptors negatively regulate α1-adrenergic receptor signalling Fulltext Access 11 Pages 2017
Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity Fulltext Access 11 Pages 2017
Early IGF-1 primes visual cortex maturation and accelerates developmental switch between NKCC1 and KCC2 chloride transporters in enriched animals Fulltext Access 11 Pages 2017
Combination strategy of PARP inhibitor with antioxidant prevent bioenergetic deficits and inflammatory changes in CCI-induced neuropathy Fulltext Access 11 Pages 2017
Prefrontal cortical GABAergic and NMDA glutamatergic regulation of delayed responding Fulltext Access 11 Pages 2017
Attenuation of Sunitinib-induced cardiotoxicity through the A3 adenosine receptor activation Fulltext Access 11 Pages 2017
Conditional deletion of Eps8 reduces hippocampal synaptic plasticity and impairs cognitive function Fulltext Access 11 Pages 2017
Molecular mechanisms controlling synaptic recruitment of GluA4 subunit-containing AMPA-receptors critical for functional maturation of CA1 glutamatergic synapses Fulltext Access 11 Pages 2017
Muscarinic acetylcholine M4 receptors play a critical role in oxotremorine-induced DARPP-32 phosphorylation at threonine 75 in isolated medium spiny neurons Fulltext Access 11 Pages 2017
A novel GLP-1/GIP dual receptor agonist protects from 6-OHDA lesion in a rat model of Parkinson's disease Fulltext Access 11 Pages 2017
Intermittent intake of rapid cocaine injections promotes robust psychomotor sensitization, increased incentive motivation for the drug and mGlu2/3 receptor dysregulation Fulltext Access 11 Pages 2017
In vivo measurement of PDE10A enzyme occupancy by positron emission tomography (PET) following single oral dose administration of PF-02545920 in healthy male subjects Fulltext Access 11 Pages 2017
Sphingosine-1-phosphate receptor therapies: Advances in clinical trials for CNS-related diseases Fulltext Access 11 Pages 2017
RF313, an orally bioavailable neuropeptide FF receptor antagonist, opposes effects of RF-amide-related peptide-3 and opioid-induced hyperalgesia in rodents Fulltext Access 11 Pages 2017
Neuroprotective and axonal outgrowth-promoting effects of tetramethylpyrazine nitrone in chronic cerebral hypoperfusion rats and primary hippocampal neurons exposed to hypoxia Fulltext Access 11 Pages 2017
Kv3.1/Kv3.2 channel positive modulators enable faster activating kinetics and increase firing frequency in fast-spiking GABAergic interneurons Fulltext Access 11 Pages 2017
Quercetin and pioglitazone synergistically reverse endothelial dysfunction in isolated aorta from fructose-streptozotocin (F-STZ)-induced diabetic rats Fulltext Access 11 Pages 2017
Losartan protects against cerebral ischemia/reperfusion-induced apoptosis through β-arrestin1-mediated phosphorylation of Akt Fulltext Access 11 Pages 2017
Dual effects of the PI3K inhibitor ZSTK474 on multidrug efflux pumps in resistant cancer cells Fulltext Access 11 Pages 2017
CS-PEG decorated PLGA nano-prototype for delivery of bioactive compounds: A novel approach for induction of apoptosis in HepG2 cell line Fulltext Access 11 Pages 2017
Na+/Ca2+ exchanger 1 inhibition abolishes ischemic tolerance induced by ischemic preconditioning in different cardiac models Fulltext Access 11 Pages 2017
Hesperidin derivative-11 inhibits fibroblast-like synoviocytes proliferation by activating Secreted frizzled-related protein 2 in adjuvant arthritis rats Fulltext Access 11 Pages 2017
Peptide screen identifies a new NADPH oxidase inhibitor: impact on cell migration and invasion Fulltext Access 11 Pages 2017
Role of carvacrol in cardioprotection against myocardial ischemia/reperfusion injury in rats through activation of MAPK/ERK and Akt/eNOS signaling pathways Fulltext Access 11 Pages 2017
Cardiovascular pharmacologyUnknown face of known drugs - what else can we expect from angiotensin converting enzyme inhibitors? Fulltext Access 11 Pages 2017
D-Ala2-GIP-glu-PAL is neuroprotective in a chronic Parkinson's disease mouse model and increases BNDF expression while reducing neuroinflammation and lipid peroxidation Fulltext Access 11 Pages 2017
Flufenamic acid protects against intestinal fluid secretion and barrier leakage in a mouse model of Vibrio cholerae infection through NF-κB inhibition and AMPK activation Fulltext Access 11 Pages 2017
Monoaminergic modulation of GABAergic transmission onto cerebellar globular cells Fulltext Access 11 Pages 2017
Anti-leukemic effects of HDACi Belinostat and HMTi 3-Deazaneplanocin A on human acute promyelocytic leukemia cells Fulltext Access 11 Pages 2017
Synthetic peptide TEKKRRETVEREKE derived from ezrin induces differentiation of NIH/3T3 fibroblasts Fulltext Access 11 Pages 2017
Compound edaravone alleviates lipopolysaccharide (LPS)-induced acute lung injury in mice Fulltext Access 11 Pages 2017
Efavirenz: What is known about the cellular mechanisms responsible for its adverse effects Fulltext Access 11 Pages 2017
Valporic acid enhances the Atrial Natriuretic Peptide (ANP) mediated anti-hypertrophic activity by modulating the Npr1 gene transcription in H9c2 cells in vitro Fulltext Access 11 Pages 2017
Comparative effects of vitamin D and methylprednisolone against ischemia/reperfusion injury of rabbit spinal cords Fulltext Access 11 Pages 2017
Vorinostat and Simvastatin have synergistic effects on triple-negative breast cancer cells via abrogating Rab7 prenylation Fulltext Access 11 Pages 2017
Berkeleyacetal C, a meroterpenoid isolated from the fungus Penicillium purpurogenum MHZ 111, exerts anti-inflammatory effects via inhibiting NF-κB, ERK1/2 and IRF3 signaling pathways Fulltext Access 11 Pages 2017
Activation of PPARγ inhibits HDAC1-mediated pulmonary arterial smooth muscle cell proliferation and its potential mechanisms Fulltext Access 11 Pages 2017
Pharmacological evaluation of metformin and N-benzylbiguanide, a novel analogue of metformin, on the vasopressor responses to adrenergic system stimulation in pithed rats with fructose-induced insulin resistance Fulltext Access 11 Pages 2017
Alpha-synuclein ferrireductase activity is detectible in vivo, is altered in Parkinson's disease and increases the neurotoxicity of DOPAL Fulltext Access 11 Pages 2017
Electrophysiological properties of neurons derived from human stem cells and iNeurons in vitro Fulltext Access 11 Pages 2017
Characterising the developmental profile of human embryonic stem cell-derived medium spiny neuron progenitors and assessing mature neuron function using a CRISPR-generated human DARPP-32WT/eGFP-AMP reporter line Fulltext Access 11 Pages 2017
Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease Fulltext Access 11 Pages 2017
Salvianolic Acids for Injection (SAFI) promotes functional recovery and neurogenesis via sonic hedgehog pathway after stroke in mice Fulltext Access 11 Pages 2017
Contrasting effects of selective MAGL and FAAH inhibition on dopamine depletion and GDNF expression in a chronic MPTP mouse model of Parkinson's disease Fulltext Access 11 Pages 2017
Sex differences in stroke across the lifespan: The role of T lymphocytes Fulltext Access 11 Pages 2017
Sequence determinants of the Caenhorhabditis elegans dopamine transporter dictating in vivo axonal export and synaptic localization Fulltext Access 11 Pages 2017
Involvement of the coatomer protein complex I in the intracellular traffic of the delta opioid receptor Fulltext Access 11 Pages 2017
Roles of afadin in the formation of the cellular architecture of the mouse hippocampus and dentate gyrus Fulltext Access 11 Pages 2017
Extracellular vesicles of the blood-brain barrier: Role in the HIV-1 associated amyloid beta pathology Fulltext Access 11 Pages 2017
Neural stem cells promote nerve regeneration through IL12-induced Schwann cell differentiation Fulltext Access 11 Pages 2017
Analgesic effects of novel lysophosphatidic acid receptor 5 antagonist AS2717638 in rodents Fulltext Access 11 Pages 2017
Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein Fulltext Access 11 Pages 2017
Time-lapse imaging of p65 and IκBα translocation kinetics following Ca2 +-induced neuronal injury reveals biphasic translocation kinetics in surviving neurons Fulltext Access 11 Pages 2017
Specific suppression of microgliosis cannot circumvent the severe neuropathology in peroxisomal β-oxidation-deficient mice Fulltext Access 11 Pages 2017
A role for astrocytes in cerebellar deficits in frataxin deficiency: Protection by insulin-like growth factor I Fulltext Access 11 Pages 2017
Parkin promotes proteasomal degradation of synaptotagmin IV by accelerating polyubiquitination Fulltext Access 11 Pages 2017
Crosstalk control and limits of physiological c-Jun N-terminal kinase activity for cell viability and neurite stability in differentiated PC12 cells Fulltext Access 11 Pages 2017
Lysine-specific demethylase-1 (LSD1) depletion disrupts monogenic and monoallelic odorant receptor (OR) expression in an olfactory neuronal cell line Fulltext Access 11 Pages 2017
High resolution methylation analysis of the HoxA5 regulatory region in different somatic tissues of laboratory mouse during development Fulltext Access 11 Pages 2017
Differential regulation of the Na+-Ca2+ exchanger 3 (NCX3) by protein kinase PKC and PKA Fulltext Access 11 Pages 2017
Original articleDNA damage induced by NADPH cytochrome P450 reductase-activated idarubicin in sensitive and multidrug resistant MCF7 breast cancer cells Fulltext Access 11 Pages 2017
Disruption of 5-HT2A-PDZ protein interaction differently affects the analgesic efficacy of SSRI, SNRI and TCA in the treatment of traumatic neuropathic pain in rats Fulltext Access 11 Pages 2017
Prevalence and influence of cys407* Grm2 mutation in Hannover-derived Wistar rats: mGlu2 receptor loss links to alcohol intake, risk taking and emotional behaviour Fulltext Access 11 Pages 2017
Pharmacological inhibition of PTEN attenuates cognitive deficits caused by neonatal repeated exposures to isoflurane via inhibition of NR2B-mediated tau phosphorylation in rats Fulltext Access 11 Pages 2017
Pramipexole enhances disadvantageous decision-making: Lack of relation to changes in phasic dopamine release Fulltext Access 11 Pages 2017
The atypical antipsychotic olanzapine disturbs depotentiation by modulating mAChRs and impairs reversal learning Fulltext Access 11 Pages 2017
Intranasal administration of recombinant Netrin-1 attenuates neuronal apoptosis by activating DCC/APPL-1/AKT signaling pathway after subarachnoid hemorrhage in rats Fulltext Access 11 Pages 2017
Methylene blue inhibits GABAA receptors by interaction with GABA binding site Fulltext Access 11 Pages 2017
Astrocytes modulate thalamic sensory processing via mGlu2 receptor activation Fulltext Access 11 Pages 2017
CRF modulates glutamate transmission in the central amygdala of naïve and ethanol-dependent rats Fulltext Access 11 Pages 2017
The great divide: Separation between in vitro and in vivo effects of PSNCBAM-based CB1 receptor allosteric modulators Fulltext Access 11 Pages 2017
Biological functions and role of mitogen-activated protein kinase activated protein kinase 2 (MK2) in inflammatory diseases Fulltext Access 11 Pages 2017
Transient inhibition of LIMKs significantly attenuated central sensitization and delayed the development of chronic pain Fulltext Access 11 Pages 2017
Physiological and pharmacological properties of inhibitory postsynaptic currents mediated by α5β1γ2, α5β2γ2 and α5β3γ2 GABAA receptors Fulltext Access 11 Pages 2017
Cannabidiol disrupts the consolidation of specific and generalized fear memories via dorsal hippocampus CB1 and CB2 receptors Fulltext Access 11 Pages 2017
Bortezomib induces neuropathic pain through protein kinase C-mediated activation of presynaptic NMDA receptors in the spinal cord Fulltext Access 11 Pages 2017
GABAA receptor positive allosteric modulators modify the abuse-related behavioral and neurochemical effects of methamphetamine in rhesus monkeys Fulltext Access 11 Pages 2017
Access to nicotine in drinking water reduces weight gain without changing caloric intake on high fat diet in male C57BL/6J mice Fulltext Access 11 Pages 2017
PTEN, a negative regulator of PI3K/Akt signaling, sustains brain stem cardiovascular regulation during mevinphos intoxication Fulltext Access 11 Pages 2017
Aripiprazole-induced adverse metabolic alterations in polyI:C neurodevelopmental model of schizophrenia in rats Fulltext Access 11 Pages 2017
α6β2 subunit containing nicotinic acetylcholine receptors exert opposing actions on rapid dopamine signaling in the nucleus accumbens of rats with high-versus low-response to novelty Fulltext Access 11 Pages 2017
A green tea polyphenol epigallocatechin-3-gallate enhances neuroregeneration after spinal cord injury by altering levels of inflammatory cytokines Fulltext Access 11 Pages 2017
Maslinic acid ameliorates NMDA receptor blockade-induced schizophrenia-like behaviors in mice Fulltext Access 11 Pages 2017